English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Structural brain changes in early-onset and late-onset depression: An update of volumetric MRI findings

Tittmann, M., Günther, T., Sacher, J., Himmerich, H., Villringer, A., Hegerl, U., et al. (2014). Structural brain changes in early-onset and late-onset depression: An update of volumetric MRI findings. International Journal of Imaging Systems and Technology, 24(2), 149-160. doi:10.1002/ima.22089.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0019-C17F-F Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002B-CDC8-8
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Tittmann, Mandy1, Author
Günther, Thomas1, Author
Sacher, Julia2, 3, Author              
Himmerich, Hubertus1, Author
Villringer, Arno2, 3, Author              
Hegerl, Ulrich1, Author
Schönknecht, Peter1, Author
Affiliations:
1Department of Psychiatry, University of Leipzig, Germany, ou_persistent22              
2Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
3Clinic for Cognitive Neurology, University of Leipzig, Germany, ou_persistent22              

Content

show
hide
Free keywords: MRI; Depression in the elderly; Hippocampus; Amygdala; Prefrontal cortex; Morphometry; Volumetry
 Abstract: Early-onset (EOD) and late-onset depression (LOD) are associated with different neuropsychological syndromes and structural brain changes. In this article, neuroimaging studies examining structural brain changes in elderly depressed patients are reviewed. The presented findings support current assumptions that depression in the elderly generally is associated with volume reductions in brain structures, notably in the hippocampus and the orbitofrontal cortex (OFC). Concerning structural cerebral differences between EOD and LOD, the review yielded conflicting results—only for OFC, but not for amygdala or hippocampus, pronounced effects in LOD than in EOD can be assumed.

Details

show
hide
Language(s): eng - English
 Dates: 2014-05-052014-06
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1002/ima.22089
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: International Journal of Imaging Systems and Technology
  Other : Int. J. Imaging Syst. Technol.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: New York : John Wiley & Sons
Pages: - Volume / Issue: 24 (2) Sequence Number: - Start / End Page: 149 - 160 Identifier: ISSN: 0899-9457
CoNE: /journals/resource/954925561596