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  Real-time flow MRI of the aorta at a resolution of 40 msec.

Joseph, A., Kowallick, J. T., Merboldt, K. D., Voit, D., Schätz, S., Zhang, S., et al. (2014). Real-time flow MRI of the aorta at a resolution of 40 msec. Journal of Magnetic Resonance Imaging, 40(1), 206-213. doi:10.1002/jmri.24328.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0019-CDDB-1 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0027-CB2C-0
Genre: Journal Article

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 Creators:
Joseph, A.1, Author              
Kowallick, J. T., Author
Merboldt, K. D.1, Author              
Voit, D.1, Author              
Schätz, S.1, Author              
Zhang, S.1, Author              
Sohns, J. M., Author
Lotz, J., Author
Frahm, J.1, Author              
Affiliations:
1Biomedical NMR Research GmbH, MPI for biophysical chemistry, Max Planck Society, ou_578634              

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Free keywords: aorta; blood flow; real-time MRI; stroke volume
 Abstract: PURPOSE: To evaluate a novel real-time phase-contrast magnetic resonance imaging (MRI) technique for the assessment of through-plane flow in the ascending aorta. MATERIALS AND METHODS: Real-time MRI was based on a radial fast low-angle shot (FLASH) sequence with about 30-fold undersampling and image reconstruction by regularized nonlinear inversion. Phase-contrast maps were obtained from two (interleaved or sequential) acquisitions with and without a bipolar velocity-encoding gradient. Blood flow in the ascending aorta was studied in 10 healthy volunteers at 3 T by both real-time MRI (15 sec during free breathing) and electrocardiogram (ECG)-synchronized cine MRI (with and without breath holding). Flow velocities and stroke volumes were evaluated using standard postprocessing software. RESULTS: The total acquisition time for a pair of phase-contrast images was 40.0 msec (TR/TE=2.86/1.93 msec, 10° flip angle, 7 spokes per image) for a nominal in-plane resolution of 1.3 mm and a section thickness of 6 mm. Quantitative evaluations of spatially averaged flow velocities and stroke volumes were comparable for real-time and cine methods when real-time MRI data were averaged across heartbeats. For individual heartbeats real-time phase-contrast MRI resulted in higher peak velocities for values above 120 cm s(-1) . CONCLUSION: Real-time phase-contrast MRI of blood flow in the human aorta yields functional parameters for individual heartbeats. When averaged across heartbeats real-time flow velocities and stroke volumes are comparable to values obtained by conventional cine MRI.

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Language(s): eng - English
 Dates: 2013-10-112014-07
 Publication Status: Published in print
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 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1002/jmri.24328
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Title: Journal of Magnetic Resonance Imaging
Source Genre: Journal
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Pages: - Volume / Issue: 40 (1) Sequence Number: - Start / End Page: 206 - 213 Identifier: -