English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Classification of object size in retinotectal microcircuits

Preuss, S. J., Trivedi, C., vom Berg-Maurer, C., Ryu, S., & Bollmann, J. H. (2014). Classification of object size in retinotectal microcircuits. Current Biology, 24(20), 2376-2385. doi:10.1016/j.cub.2014.09.012.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0023-D47F-0 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0026-A50A-3
Genre: Journal Article

Files

show Files
hide Files
:
CurrentBiol_2014_18.Sept_e1.pdf (Any fulltext), 3MB
 
File Permalink:
-
Name:
CurrentBiol_2014_18.Sept_e1.pdf
Description:
-
Visibility:
Restricted (Max Planck Institute for Medical Research, MHMF; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Creators

show
hide
 Creators:
Preuss, Stephanie J.1, Author              
Trivedi, Chintan1, Author              
vom Berg-Maurer, Colette2, Author              
Ryu, Soojin2, Author              
Bollmann, Johann H.1, Author              
Affiliations:
1Department of Biomedical Optics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497699              
2Max Planck Research Group Developmental Genetics of the nervous system (Soojin Ryu), Max Planck Institute for Medical Research, Max Planck Society, ou_1497724              

Content

show
hide
Free keywords: -
 Abstract: Background A principal task of the visual system is to detect and classify moving objects in the visual environment. Information about the size of an object is critical for selecting appropriate behavioral responses. Object size is encoded in retinal ganglion cell (RGC) activity. Little is known, however, about how inputs from the multitude of RGC subtypes are distributed to higher visual centers and how information is combined from these feature-selective inputs. Results Here we show that in the zebrafish optic tectum, prey- or predator-like moving targets evoke activity in distinct groups of RGC fibers dependent on target size, demonstrating a retinal origin of tectal size classification. Small-size-selective retinal inputs are relatively more frequent in the most superficial layer of the tectal neuropil, whereas large-size-selective inputs predominate in deeper layers. Monostratified superficial interneurons (SINs) process large-size- and small-size-selective signals dependent on their dendritic target layer, consistent with the retinal input organization. Further downstream, small- and large-sized objects are encoded in population activity of separate sets of tectal neurons. Conclusions Ethologically relevant size classes are preferentially processed in different layers of the tectal neuropil. The tectum categorizes visual targets on the basis of retinally computed size information, suggesting a critical role in visually guided response selection.

Details

show
hide
Language(s): eng - English
 Dates: 2014-08-312014-08-222014-09-012014-09-182014-10-20
 Publication Status: Published in print
 Pages: 10
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1016/j.cub.2014.09.012
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Current Biology
  Other : Curr. Biol.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: London, UK : Cell Press
Pages: - Volume / Issue: 24 (20) Sequence Number: - Start / End Page: 2376 - 2385 Identifier: ISSN: 0960-9822
CoNE: https://pure.mpg.de/cone/journals/resource/954925579107