English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Biosynthesis of 8-hydroxyquinoline-2-carboxylic acid, an iron chelator from the gut of the lepidopteran Spodoptera littoralis

Pesek, J., Svoboda, J., Sattler, M., Bartram, S., & Boland, W. (2014). Biosynthesis of 8-hydroxyquinoline-2-carboxylic acid, an iron chelator from the gut of the lepidopteran Spodoptera littoralis. Organic & Biomolecular Chemistry, 13(1), 178-184. doi:10.1039/c4ob01857e.

Item is

Files

show Files
hide Files
:
BOL609.pdf (Publisher version), 346KB
 
File Permalink:
-
Name:
BOL609.pdf
Description:
-
Visibility:
Restricted (Max Planck Institute for Chemical Ecology, MJCO; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-
:
BOL609s1.pdf (Supplementary material), 660KB
 
File Permalink:
-
Name:
BOL609s1.pdf
Description:
-
Visibility:
Restricted (Max Planck Institute for Chemical Ecology, MJCO; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Pesek, Jelena1, Author              
Svoboda, Jiri1, Author              
Sattler, Martina1, Author              
Bartram, Stefan1, Author              
Boland, Wilhelm1, Author              
Affiliations:
1Department of Bioorganic Chemistry, Prof. Dr. W. Boland, MPI for Chemical Ecology, Max Planck Society, ou_24028              

Content

show
hide
Free keywords: -
 Abstract: In the regurgitate (foregut content) of Spodoptera larvae we found high concentrations (0.5–5 mM) of 8-hydroxyquinoline-2-carboxylic acid (8-HQA). In a survey of different lepidopteran species, this compound was only detected in species belonging to the family of Noctuidae. 8-HQA was shown to derive from tryptophan metabolism. The amount of 8-HQA in the regurgitate was strongly dependent on the tryptophan content of the diet. In the insect 8-HQA is generated from tryptophan via kynurenine and 3-hydroxykynurenine. 8-HQA is produced by the larvae and not by their commensal gut bacteria. Analysis of different life stages of Spodoptera larvae revealed that 8-HQA is formed during the larval stage, probably acting as an iron chelator to control the gut microbiome.

Details

show
hide
Language(s):
 Dates: 2014-10-082014-10-092014-12-03
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: Other: BOL609
DOI: 10.1039/c4ob01857e
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Organic & Biomolecular Chemistry
  Other : Organic and Biomolecular Chemistry
  Abbreviation : Org. Biomol. Chem.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Cambridge : Royal Society of Chemistry
Pages: - Volume / Issue: 13 (1) Sequence Number: - Start / End Page: 178 - 184 Identifier: ISSN: 1477-0520
CoNE: https://pure.mpg.de/cone/journals/resource/954925269322