Single particle imaging with soft X-rays at the linac coherent light source

Martin, Andrew V.; Andreasson, Jakob; Aquila, Andrew; Bajt, Saša; Barends, Thomas; Barthelmess, Miriam; Barty, Anton; Benner, W. Henry; Bostedt, Christoph; Bozek, John D.; Bucksbaum, Phillip; Caleman, Carl; Coppola, Nicola; Deponte, Daniel P.; Ekeberg, Tomas; Epp, Sascha W.; Erk, Benjamin; Farquar, George R.; Fleckenstein, Holger; Foucar, Lutz; Frank, Matthias; Gumprecht, Lars; Hampton, Christina Y.; Hantke, Max; Hartmann, Andreas; Hartmann, Elisabeth; Hartmann, Robert; Hau−Riege, Stephan P.; Hauser, Günther; Holl, Peter; Hömke, André; Jönsson, Olof; Kassemeyer, Stephan; Kimmel, Nils; Kiskinova, Maya; Krasniqi, Faton; Krzywinski, Jacek; Liang, Mengning; Loh, Ne−Te Duane; Lomb, Lukas; Maia, Filipe R. N. C.; Marchesini, Stefano; Messerschmidt, Marc; Nass, Karol; Odic, Duško; Pedersoli, Emanuele; Reich, Christian; Rolles, Daniel; Rudek, Benedikt; Rudenko, Artem; Schmidt, Carlo; Schultz, Joachim; Seibert, M. Marvin; Shoeman, Robert L.; Sierra, Raymond G.; Soltau, Heike; Starodub, Dmitri; Steinbrener, Jan; Stellato, Francesco; Strüder, Lothar; Svenda, Martin; Tobias, Herbert; Ullrich, Joachim; Weidenspointner, Georg; Westphal, Daniel; White, Thomas A.; Williams, Garth; Hajdu, Janos; Schlichting, Ilme; Bogan, Michael J.; Chapman, Henry N.

doi:10.1117/12.886754

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Single particle imaging with soft X-rays at the linac coherent light source

Martin, A. V., Andreasson, J., Aquila, A., Bajt, S., Barends, T., Barthelmess, M., et al. (2011). Single particle imaging with soft X-rays at the linac coherent light source. Proceedings of SPIE, 8078: 807809, pp. 1-9. doi:10.1117/12.886754.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0024-1D9D-A Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0024-1D9E-8

Genre: Journal Article

Alternative Title : Single particle imaging with soft X-rays at the linac coherent light source

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Martin, Andrew V., Author
Andreasson, Jakob, Author
Aquila, Andrew, Author
Bajt, Saša, Author
Barends, Thomas¹, Author
Barthelmess, Miriam, Author
Barty, Anton, Author
Benner, W. Henry, Author
Bostedt, Christoph, Author
Bozek, John D., Author
Bucksbaum, Phillip, Author
Caleman, Carl, Author
Coppola, Nicola, Author
Deponte, Daniel P., Author
Ekeberg, Tomas, Author
Epp, Sascha W., Author
Erk, Benjamin¹, Author
Farquar, George R., Author
Fleckenstein, Holger, Author
Foucar, Lutz¹, Author
Frank, Matthias, AuthorGumprecht, Lars, AuthorHampton, Christina Y., AuthorHantke, Max, AuthorHartmann, Andreas, AuthorHartmann, Elisabeth¹, Author         Hartmann, Robert, AuthorHau−Riege, Stephan P., AuthorHauser, Günther, AuthorHoll, Peter, AuthorHömke, André, AuthorJönsson, Olof, AuthorKassemeyer, Stephan¹, Author         Kimmel, Nils, AuthorKiskinova, Maya, AuthorKrasniqi, Faton¹, Author         Krzywinski, Jacek, AuthorLiang, Mengning, AuthorLoh, Ne−Te Duane, AuthorLomb, Lukas¹, Author         Maia, Filipe R. N. C., AuthorMarchesini, Stefano, AuthorMesserschmidt, Marc, AuthorNass, Karol¹, Author         Odic, Duško, AuthorPedersoli, Emanuele, AuthorReich, Christian, AuthorRolles, Daniel¹, Author         Rudek, Benedikt¹, Author         Rudenko, Artem, AuthorSchmidt, Carlo, AuthorSchultz, Joachim, AuthorSeibert, M. Marvin, AuthorShoeman, Robert L.¹, Author         Sierra, Raymond G., AuthorSoltau, Heike, AuthorStarodub, Dmitri, AuthorSteinbrener, Jan¹, Author         Stellato, Francesco, AuthorStrüder, Lothar, AuthorSvenda, Martin, AuthorTobias, Herbert, AuthorUllrich, Joachim, AuthorWeidenspointner, Georg, AuthorWestphal, Daniel, AuthorWhite, Thomas A., AuthorWilliams, Garth, AuthorHajdu, Janos, AuthorSchlichting, Ilme¹, Author         Bogan, Michael J., AuthorChapman, Henry N., Author more..

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1Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Max Planck Society, ou_1497700

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Abstract: Results of coherent diffractive imaging experiments performed with soft X−rays (1−2 keV) at the Linac Coherent Light Source are presented. Both organic and inorganic nano−sized objects were injected into the XFEL beam as an aerosol focused with an aerodynamic lens. The high intensity and femtosecond duration of X−ray pulses produced by the Linac Coherent Light Source allow structural information to be recorded by X−ray diffraction before the particle is destroyed. Images were formed by using iterative methods to phase single shot diffraction patterns. Strategies for improving the reconstruction methods have been developed. This technique opens up exciting opportunities for biological imaging, allowing structure determination without freezing, staining or crystallization

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Language(s): eng - English

Dates: Accepted: 2011-04-20Date issued: 2011-05-20

Publication Status: Issued

Pages: 9

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Rev. Type: Peer

Identifiers: eDoc: 664435
DOI: 10.1117/12.886754
Other: 7754

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Title: Proceedings of SPIE

Alternative Title : Proceedings of SPIE

Source Genre: Journal

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Pages: - Volume / Issue: 8078 Sequence Number: 807809 Start / End Page: 1 - 9 Identifier: ISSN: 0277-786X