English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  A-to-I RNA Editing: Effects on Proteins Key to Neural Excitability

Rosenthal, J. J. C., & Seeburg, P. H. (2012). A-to-I RNA Editing: Effects on Proteins Key to Neural Excitability. Neuron, 74(3), 432-439. doi:10.1016/j.neuron.2012.04.010.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0024-1ECF-0 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0024-1ED0-A
Genre: Journal Article
Alternative Title : A-to-I RNA Editing: Effects on Proteins Key to Neural Excitability

Files

show Files
hide Files
:
Neuron_74_2012_432.pdf (Any fulltext), 499KB
 
File Permalink:
-
Name:
Neuron_74_2012_432.pdf
Description:
-
Visibility:
Restricted (Max Planck Institute for Medical Research, MHMF; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Description:
-

Creators

show
hide
 Creators:
Rosenthal, Joshua J. C., Author
Seeburg, Peter H.1, Author              
Affiliations:
1Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              

Content

show
hide
Free keywords: -
 Abstract: RNA editing by adenosine deamination is a process used to diversify the proteome. The expression of ADARs, the editing enzymes, is ubiquitous among true metazoans, and so adenosine deamination is thought to be universal. By changing codons at the level of mRNA, protein function can be altered, perhaps in response to physiological demand. Although the number of editing sites identified in recent years has been rising exponentially, their effects on protein function, in general, are less well understood. This review assesses the state of the field and highlights particular cases where the biophysical alterations and functional effects caused by RNA editing have been studied in detail

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Neuron
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Cambridge, Mass. : Cell Press
Pages: - Volume / Issue: 74 (3) Sequence Number: - Start / End Page: 432 - 439 Identifier: ISSN: 0896-6273
CoNE: https://pure.mpg.de/cone/journals/resource/954925560565