English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
 
 
DownloadE-Mail
  The mzTab Data Exchange Format: Communicating Mass-spectrometry-based Proteomics and Metabolomics Experimental Results to a Wider Audience

Griss, J., Jones, A. R., Sachsenberg, T., Walzer, M., Gatto, L., Hartler, J., et al. (2014). The mzTab Data Exchange Format: Communicating Mass-spectrometry-based Proteomics and Metabolomics Experimental Results to a Wider Audience. MOLECULAR & CELLULAR PROTEOMICS, 13(10), 2765-2775. doi:10.1074/mcp.O113.036681.

Item is

Files

show Files
hide Files
:
Mol Cell Proteomics-2014-Griss-2765-75.pdf (Any fulltext), 2MB
Name:
Mol Cell Proteomics-2014-Griss-2765-75.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
open access article - Author's Choice
License:
-

Locators

show

Creators

show
hide
 Creators:
Griss, Johannes1, Author
Jones, Andrew R.1, Author
Sachsenberg, Timo1, Author
Walzer, Mathias1, Author
Gatto, Laurent1, Author
Hartler, Jürgen1, Author
Thallinger, Gerhard G.1, Author
Salek, Reza M.1, Author
Steinbeck, Christoph1, Author
Neuhauser, Nadin2, Author              
Cox, Jürgen2, Author              
Neumann, Steffen1, Author
Fan, Jun1, Author
Reisinger, Florian1, Author
Xu, Qing-Wei1, Author
del Toro, Noemi1, Author
Perez-Riverol, Yasset1, Author
Ghali, Fawaz1, Author
Bandeira, Nuno1, Author
Xenarios, Ioannis1, Author
Kohlbacher, Oliver1, AuthorVizcaino, Juan Antonio1, AuthorHermjakob, Henning1, Author more..
Affiliations:
1external, ou_persistent22              
2Mann, Matthias / Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565159              

Content

show
hide
Free keywords: PROTEIN IDENTIFICATION DATA; MZQUANTML DATA STANDARD; PEPTIDE IDENTIFICATION; DATA SUBMISSION; JAVA INTERFACE; MS DATA; PSI; REPRESENTATION; QUANTITATION; INFORMATION
 Abstract: The HUPO Proteomics Standards Initiative has developed several standardized data formats to facilitate data sharing in mass spectrometry (MS)-based proteomics. These allow researchers to report their complete results in a unified way. However, at present, there is no format to describe the final qualitative and quantitative results for proteomics and metabolomics experiments in a simple tabular format. Many downstream analysis use cases are only concerned with the final results of an experiment and require an easily accessible format, compatible with tools such as Microsoft Excel or R. We developed the mzTab file format for MS-based proteomics and metabolomics results to meet this need. mzTab is intended as a lightweight supplement to the existing standard XML-based file formats (mzML, mzIdentML, mzQuantML), providing a comprehensive summary, similar in concept to the supplemental material of a scientific publication. mzTab files can contain protein, peptide, and small molecule identifications together with experimental metadata and basic quantitative information. The format is not intended to store the complete experimental evidence but provides mechanisms to report results at different levels of detail. These range from a simple summary of the final results to a representation of the results including the experimental design. This format is ideally suited to make MS-based proteomics and metabolomics results available to a wider biological community outside the field of MS. Several software tools for proteomics and metabolomics have already adapted the format as an output format. The comprehensive mzTab specification document and extensive additional documentation can be found online.

Details

show
hide
Language(s): eng - English
 Dates: 2014-10
 Publication Status: Published in print
 Pages: 11
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: ISI: 000343228300018
DOI: 10.1074/mcp.O113.036681
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: MOLECULAR & CELLULAR PROTEOMICS
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: 9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3996 USA : AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
Pages: - Volume / Issue: 13 (10) Sequence Number: - Start / End Page: 2765 - 2775 Identifier: ISSN: 1535-9476