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  Calcium permeability of glutamate-gated channels in the central nervous system

Burnashev, N. (1996). Calcium permeability of glutamate-gated channels in the central nervous system. Current Opinion in Neurobiology, 6(3), 311-317. Retrieved from http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd%3DRetrieve%26db%3DPubMed%26list_uids%3D8794087%26dopt%3DAbstract.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0024-40C2-D Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0024-40C3-B
Genre: Journal Article
Alternative Title : Calcium permeability of glutamate-gated channels in the central nervous system

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CurrOpinNeurobiol_6_1996_311.pdf (Any fulltext), 640KB
 
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CurrOpinNeurobiol_6_1996_311.pdf
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 Creators:
Burnashev, Nail1, Author           
Affiliations:
1Department of Cell Physiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497701              

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 Abstract: Molecular cloning of ionotropic glutamate receptors and the development of new measurement techniques have significantly advanced our understanding of the molecular mechanisms controlling ligand−mediated entry of Ca2+ into neurons of the mammalian CNS. Recent studies have demonstrated that various types of glutamate receptors expressed in different nerve cells are permeable to Ca2+ to variable extents, depending on the structural peculiarities of the subunits and their composition in a particular cell. This diversity provides a regulable pathway for Ca2+ entry during synaptic transmission. The fractional contribution of this Ca2+ to the total synaptic current might be a substantial means of elevating the intracellular Ca2+ concentration over a wide temporal range

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Language(s): eng - English
 Dates: 1996-06
 Publication Status: Issued
 Pages: 7
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 666458
URI: http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd%3DRetrieve%26db%3DPubMed%26list_uids%3D8794087%26dopt%3DAbstract
Other: 4549
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Title: Current Opinion in Neurobiology
  Other : Curr. Opin.Neurobiol.
Source Genre: Journal
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Publ. Info: New York, NY : Elsevier Current Trends
Pages: - Volume / Issue: 6 (3) Sequence Number: - Start / End Page: 311 - 317 Identifier: ISSN: 0959-4388
CoNE: https://pure.mpg.de/cone/journals/resource/954925578066