Exercise Boosts Hippocampal Volume by Preventing Early Age-Related Gray Matter 
Loss

Fuss, Johannes; Biedermann, Sarah V.; Falfan-Melgoza, Claudia; Auer, Matthias K.; Zheng, Lei; Steinle, Joerg; Hoerner, Felix; Sartorius, Alexander; Ende, Gabriele; Weber-Fahr, Wolfgang; Gass, Peter

doi:10.1002/hipo.22227

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Exercise Boosts Hippocampal Volume by Preventing Early Age-Related Gray Matter Loss

Fuss, J., Biedermann, S. V., Falfan-Melgoza, C., Auer, M. K., Zheng, L., Steinle, J., et al. (2014). Exercise Boosts Hippocampal Volume by Preventing Early Age-Related Gray Matter Loss. HIPPOCAMPUS, 24(2), 131-134. doi:10.1002/hipo.22227.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0026-ADFE-C Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0026-ADFF-A

Genre: Journal Article

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Creators:
Fuss, Johannes¹, Author
Biedermann, Sarah V.¹, Author
Falfan-Melgoza, Claudia¹, Author
Auer, Matthias K.², Author
Zheng, Lei¹, Author
Steinle, Joerg¹, Author
Hoerner, Felix¹, Author
Sartorius, Alexander¹, Author
Ende, Gabriele¹, Author
Weber-Fahr, Wolfgang¹, Author
Gass, Peter¹, Author

Affiliations:
1external, ou_persistent22
2Dept. Clinical Research, Max Planck Institute of Psychiatry, Max Planck Society, ou_2035296

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Abstract: Recently, a larger hippocampus was found in exercising mice and men. Here we studied the morphological underpinnings in wheel running mice by longitudinal magnetic resonance imaging. Voxel-based morphometry revealed that running increases hippocampal volume by inhibiting an early age-related gray matter loss. Disruption of neurogenesis-related neuroplasticity by focalized irradiation is sufficient to block positive effects of exercise on macroscopic brain morphology. (c) 2013 Wiley Periodicals, Inc.

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Language(s): eng - English

Dates: Published Online: 2013-10-28Date issued: 2014-02

Publication Status: Issued

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Identifiers: ISI: 000329879300001
DOI: 10.1002/hipo.22227

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Title: HIPPOCAMPUS

Source Genre: Journal

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Publ. Info: Wiley Periodicals, Inc.

Pages: - Volume / Issue: 24 (2) Sequence Number: - Start / End Page: 131 - 134 Identifier: ISSN: 1050-9631