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  PICKScreens, A New Database for the Comparison of Crystallization Screens for Biological Macromolecules

Hedderich, T., Marcia, M., Köpke, J., & Michel, H. (2011). PICKScreens, A New Database for the Comparison of Crystallization Screens for Biological Macromolecules. Crystal Growth & Design, 11(2), 488-491. doi:10.1021/cg101267n.

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 Creators:
Hedderich, Tanja1, Author           
Marcia, Marco1, Author           
Köpke, Jürgen1, Author           
Michel, Hartmut1, Author           
Affiliations:
1Department of Molecular Membrane Biology, Max Planck Institute of Biophysics, Max Planck Society, ou_2068290              

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 Abstract: Extensive screening during crystallization trials is necessary, especially for challenging but interesting targets, that is, large multisubunit complexes or membrane proteins. Producing high amounts of such macromolecules is difficult, so it is important to perform screening efficiently. However, commercial screens are redundant, leading to unnecessary or unwanted sample consumption, and cannot be visually compared, because the manufacturers’ formulations are not formatted uniformly. PICKScreens, a database reporting Profile of Identities among Crystallization Kit Screens, will help crystallographers “pick” screens in a more rational manner, minimizing sample consumption and hopefully enhancing their success rate.

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Language(s): eng - English
 Dates: 2010-11-292010-09-272010-12-312011-02-02
 Publication Status: Published in print
 Pages: 4
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1021/cg101267n
 Degree: -

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Title: Crystal Growth & Design
  Other : Cryst. Growth Des.
Source Genre: Journal
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Publ. Info: Washington, DC : American Chemical Society
Pages: - Volume / Issue: 11 (2) Sequence Number: - Start / End Page: 488 - 491 Identifier: ISSN: 1528-7483
CoNE: https://pure.mpg.de/cone/journals/resource/110978984570353