English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Rescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyase

Benjdia, A., Heil, K., Winkler, A., Carell, T., & Schlichting, I. (2014). Rescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyase. Chemical Communications, 50(91), 14201-14204. doi:10.1039/C4CC05158K.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0024-947D-E Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0024-94B2-1
Genre: Journal Article

Files

show Files
hide Files
:
ChemCommunic_50_2014_14201.pdf (Any fulltext), 2MB
 
File Permalink:
-
Name:
ChemCommunic_50_2014_14201.pdf
Description:
-
Visibility:
Restricted (Max Planck Institute for Medical Research, MHMF; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Description:
-
Locator:
http://dx.doi.org/10.1039/C4CC05158K (Any fulltext)
Description:
-

Creators

show
hide
 Creators:
Benjdia, Alhosna1, Author              
Heil, Korbinian, Author
Winkler, Andreas1, Author              
Carell, Thomas, Author
Schlichting, Ilme1, Author              
Affiliations:
1Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Max Planck Society, ou_1497700              

Content

show
hide
Free keywords: -
 Abstract: The radical SAM enzyme, spore photoproduct lyase, requires an H-atom transfer (HAT) pathway to catalyze DNA repair. By rational engineering, we demonstrate that it is possible to rewire its HAT pathway, a first step toward the development of novel catalysts based on the radical SAM enzyme scaffold.

Details

show
hide
Language(s): eng - English
 Dates: 2014-07-042014-09-182014-09-192014-11-25
 Publication Status: Published in print
 Pages: 4
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Chemical Communications
  Other : Chem. Commun.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Cambridge, UK : Royal Society of Chemistry
Pages: - Volume / Issue: 50 (91) Sequence Number: - Start / End Page: 14201 - 14204 Identifier: ISSN: 1359-7345
CoNE: https://pure.mpg.de/cone/journals/resource/954928495413