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  Amorfrutins: A promising class of natural products that are beneficial to health

Sauer, S. (2014). Amorfrutins: A promising class of natural products that are beneficial to health. ChemBioChem: A European Journal of Chemical Biology, 15(9), 1231-1238. doi:10.1002/cbic.201402124.

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© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
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 Creators:
Sauer, Sascha1, Author              
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1Nutrigenomics and Gene Regulation (Sascha Sauer), Independent Junior Research Groups (OWL), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1479662              

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Free keywords: gene expression; ligand effects; metabolic diseases; nutraceuticals; receptors
 Abstract: The incidence of complex noncommunicable diseases has strongly increased over the last several decades in the US, Europe and other parts of the world that have adopted a western lifestyle (M. Ezzati, E. Riboli, Science- 2012, 337, 1482-1487; S. Smyth, A. Heron, Nat. Med.- 2006, 12, 75). Despite considerable investment in the development of new types of drugs, options for the treatment of many common diseases remain inadequate. If current trends prevail, the rising incidence of disorders such as obesity and type 2 diabetes mellitus (T2DM) will soon result in an unsustainable burden on society (World Health Organization Technical Report Series- 2000, 894, i-xii, 1-253). Given the difficulty of treating fully developed complex disorders, new strategies for early intervention and prevention of common diseases are of great interest. Dietary natural products with beneficial effects, such as the recently described antidiabetic and lipid-lowering amorfrutins, could pave the way for efficiently treating and preventing metabolic and other complex diseases (C. Weidner, et al. Proc. Natl. Acad. Sci. USA- 2012, 109, 7257-7262).

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Language(s): eng - English
 Dates: 2014-06-042014-06-16
 Publication Status: Published in print
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 Rev. Type: Peer
 Identifiers: DOI: 10.1002/cbic.201402124
ISSN: 1439-7633 (Electronic)1439-4227 (Print)
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Title: ChemBioChem : A European Journal of Chemical Biology
  Other : ChemBioChem
Source Genre: Journal
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Publ. Info: Weinheim, Germany : Wiley-VCH
Pages: - Volume / Issue: 15 (9) Sequence Number: - Start / End Page: 1231 - 1238 Identifier: ISSN: 1439-4227
CoNE: https://pure.mpg.de/cone/journals/resource/110978984568897_1