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Free keywords:
alkynes; copper; cycloaddition; gold; tandem reactions
Abstract:
Being unconventional: Although conventional metal-catalyzed [4+2] cycloadditions of inactivated dienynes are known to proceed by an oxidative cyclization/insertion mechanism, two entirely different pathways also result in formal Diels–Alder reactions (see scheme). These alternative mechanisms open new vistas for further functionalization of the products, as exemplified by an unprecedented cycloaddition/alkylation cascade.