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  A New Technology for Applanation Free Corneal Trephination: The Picosecond Infrared Laser (PIRL)

Linke, S. J., Frings, A., Ren, L., Gomolka, A., Schumacher, U., Reimer, R., et al. (2015). A New Technology for Applanation Free Corneal Trephination: The Picosecond Infrared Laser (PIRL). PLoS One, 10(3): 0120944. doi:10.1371/journal.pone.0120944.

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journal.pone.0120944.pdf (Publisher version), 4MB
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Linke et al.

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 Creators:
Linke, Stephan J.1, Author
Frings, Andreas1, Author
Ren, Ling2, Author           
Gomolka, Amadeus1, Author
Schumacher, Udo3, Author
Reimer, Rudolph4, Author
Hansen, Nils-Owe2, Author           
Jowett, Nathan2, 5, Author
Richard, Gisbert1, Author
Miller, R. J. Dwayne2, Author           
Affiliations:
1Department of Ophthalmology, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany, ou_persistent22              
2Miller Group, Atomically Resolved Dynamics Department, Max Planck Institute for the Structure and Dynamics of Matter, Max Planck Society, ou_1938288              
3Department of Anatomy and Experimental Morphology, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany, ou_persistent22              
4Heinrich Pette Institute, Leibniz Institute for Experimental Virology, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany, ou_persistent22              
5Department of Otorhinolaryngology, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany, ou_persistent22              

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Free keywords: cornea; lasers; laser beams; vibration; corneal transplantation; penetrating keratoplasty; scanning electron microscopy; surgical and invasive medical procedures
 Abstract: The impact of using a Femtosecond laser on final functional results of penetrating keratoplasty is low. The corneal incisions presented here result from laser ablations with ultrafast desorption by impulsive vibrational excitation (DIVE). The results of the current study are based on the first proof-of-principle experiments using a mobile, newly introduced picosecond infrared laser system, and indicate that wavelengths in the mid-infrared range centered at 3 μm are efficient for obtaining applanation-free deep cuts on porcine corneas.

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Language(s): eng - English
 Dates: 2014-09-082015-01-292015-03-17
 Publication Status: Published online
 Pages: 12
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1371/journal.pone.0120944
PMC: PMC4363595
 Degree: -

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Title: PLoS One
Source Genre: Journal
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Publ. Info: San Francisco, CA : Public Library of Science
Pages: - Volume / Issue: 10 (3) Sequence Number: 0120944 Start / End Page: - Identifier: ISSN: 1932-6203
CoNE: https://pure.mpg.de/cone/journals/resource/1000000000277850