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  Learning about human population history from ancient and modern genomes

Stoneking, M., & Krause, J. (2011). Learning about human population history from ancient and modern genomes. Nature Reviews Genetics, 12(9): 3029, pp. 603-614. doi:10.1038/nrg3029.

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 Creators:
Stoneking, Mark1, 2, Author           
Krause, Johannes3, Author           
Affiliations:
1Human Population History, Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society, ou_2074313              
2Department of Evolutionary Genetics, Max Planck Institute for Evolutionary Anthropology, Max Planck Society, ou_1497672              
3External Organizations, ou_persistent22              

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Free keywords: Anthropology. Evolutionary biology, Genomics, Next-generation sequencing, Population genetics
 Abstract: Genome-wide data, both from SNP arrays and from complete genome sequencing, are becoming increasingly abundant and are now even available from extinct hominins. These data are providing new insights into population history; in particular, when combined with model-based analytical approaches, genome-wide data allow direct testing of hypotheses about population history. For example, genome-wide data from both contemporary populations and extinct hominins strongly support a single dispersal of modern humans from Africa, followed by two archaic admixture events: one with Neanderthals somewhere outside Africa and a second with Denisovans that (so far) has only been detected in New Guinea. These new developments promise to reveal new stories about human population history, without having to resort to storytelling.

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Language(s): eng - English
 Dates: 2011-09-112011-09
 Publication Status: Issued
 Pages: 12
 Publishing info: -
 Table of Contents: Methods for obtaining genome-scale data
High-throughput sequencing of ancient genomes.
Assembly of ancient genomes.
Targeted approaches using SNP arrays.
Targeted DNA hybridization capture.
Making inferences about population history
Unsupervised approaches.
Model-based approaches.
Admixture.
What have we learned so far?
Hominin relationships.
African origin of modern humans.
Dispersal from Africa: replacement or assimilation?
Dispersal from Africa: how many times, and which way did they go?
Other migrations of modern humans.
What more can we expect to learn?
Ancient hominin admixture.
Ancient modern humans.
More data from contemporary populations.
New methods for inferring history from genome-wide data.
 Rev. Type: Peer
 Identifiers: ISI: 000294004100007
DOI: 10.1038/nrg3029
Other: shh0011
 Degree: -

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Title: Nature Reviews Genetics
Source Genre: Journal
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Publ. Info: London, UK : Nature Pub. Group
Pages: - Volume / Issue: 12 (9) Sequence Number: 3029 Start / End Page: 603 - 614 Identifier: ISSN: 1471-0056
CoNE: https://pure.mpg.de/cone/journals/resource/110985821000939