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  Interactions and visualization of bio-mimetic membrane detachment at smooth and nano-rough gold electrode surfaces

Donaldson Jr., S. H., Valtiner, M., Gebbie, M. A., Harada, J. K., & Israelachvili, J. N. (2013). Interactions and visualization of bio-mimetic membrane detachment at smooth and nano-rough gold electrode surfaces. Soft Matter, 9(21), 5231-5238. doi:10.1039/c3sm27217f.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0026-BB14-5 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0026-BB15-3
Genre: Journal Article

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 Creators:
Donaldson Jr., Stephen H.1, Author              
Valtiner, Markus2, 3, Author              
Gebbie, Matthew A.4, Author              
Harada, Jaye K.5, Author              
Israelachvili, Jacob N.1, 6, Author              
Affiliations:
1Department of Chemical Engineering, University of California, Santa Barbara, CA 93106-5080, USA, ou_persistent22              
2Interaction Forces and Functional Materials, Interface Chemistry and Surface Engineering, Max-Planck-Institut für Eisenforschung GmbH, Max Planck Society, ou_1863357              
3Department of Chemical Engineering, University of California, Santa Barbara, CA 93106, USA, ou_persistent22              
4Materials Department, University of California, Santa Barbara, CA 93116, USA, ou_persistent22              
5Materials Research Laboratory, University of California, Santa Barbara, CA, USA, ou_persistent22              
6Materials Department, University of California, Santa Barbara, CA, USA, ou_persistent22              

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Free keywords: Chemical interactions; Hydrophobic interactions; Interaction forces; Interfacial behaviors; Membrane interactions; Multi-scale approaches; Quantitative agreement; Surface forces apparatus
 Abstract: Non-specific physical and specific chemical interactions of cells, bacteria, and biomembranes with non-biological target surfaces (e. g., metallic and metal oxides) are crucial in determining the interfacial behavior (interaction forces, adhesion, local deformations and structuring) of many bio- and nano-inspired materials. Knowledge of the governing interactions provides physicochemical understanding of biological systems, and enables engineering of new nano-systems for biomaterials or biomedical benefit. We have directly measured and visualized membrane adhesion and detachment at nanoscopic and extended rough gold electrode surfaces through a multi-scale approach: interactions and contact mechanics measured by surface forces apparatus (SFA) are in quantitative agreement with atomic force microscopy (AFM) measurements, both of which show that membranes can strongly adhere to rough gold surfaces and asperities via specific amine-gold binding and non-specific hydrophobic interactions. The results give insights into membrane interactions at smooth and rough metallic surfaces, and provide a basis for improved design of nanoparticle and extended surface biomaterials.

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Language(s): eng - English
 Dates: 2013-06-11
 Publication Status: Published in print
 Pages: 8
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: ISI: 000318562800013
DOI: 10.1039/c3sm27217f
 Degree: -

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Title: Soft Matter
  Abbreviation : Soft Matter
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Cambridge, UK : Royal Society of Chemistry
Pages: - Volume / Issue: 9 (21) Sequence Number: - Start / End Page: 5231 - 5238 Identifier: ISSN: 1744-683X
CoNE: /journals/resource/1744-683X