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  Redesigning antidepressant drug discovery. [Guest Editorial]

Holsboer, F. (2014). Redesigning antidepressant drug discovery. [Guest Editorial]. Dialogues in clinical neuroscience, 16(1), 5-7.

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 Creators:
Holsboer, Florian1, Author           
Affiliations:
1Max Planck Institute of Psychiatry, Max Planck Society, ou_1607137              

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 Abstract: Antidepressant drug discovery and development have been put on hold by many pharmaceutical companies. The main reason for this is the negative efficacy studies with novel specific drugs. Here I argue that the main obstacles are the absence of gene tests and biomarkers as an integral part of a diagnostic process. Further, too much emphasis has been put on validating drug candidates in animal models of psychiatric disorders. A more rapid transfer of drug candidates into human research is necessary to overcome current obstacles that prevent the discovery of next-generation antidepressants.

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Language(s): eng - English
 Dates: 2014-01
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: ISI: 24733967
 Degree: -

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Title: Dialogues in clinical neuroscience
Source Genre: Journal
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Publ. Info: Suresnes Cedex, France : Institut La Conference Hippocrate
Pages: - Volume / Issue: 16 (1) Sequence Number: - Start / End Page: 5 - 7 Identifier: -