English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Imperceptible somatosensory stimulation alters sensorimotor background rhythm and connectivity

Nierhaus, T., Forschack, N., Piper, S. K., Holtze, S., Krause, T., Taskin, B., et al. (2015). Imperceptible somatosensory stimulation alters sensorimotor background rhythm and connectivity. The Journal of Neuroscience, 35(15), 5917-5925. doi:10.1523/JNEUROSCI.3806-14.2015.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0026-BC87-1 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-78EE-B
Genre: Journal Article

Files

show Files
hide Files
:
Nierhaus et al_2015_Imperceptible Somatosensory Stimulation Alters Sensorimotor Background Rhythm_The Journal of Neuroscience.pdf (Publisher version), 3MB
Name:
Nierhaus et al_2015_Imperceptible Somatosensory Stimulation Alters Sensorimotor Background Rhythm_The Journal of Neuroscience.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
2015
Copyright Info:
This work is licensed under a Creative Commons Attribution-Noncommercial 3.0 License.

Locators

show

Creators

show
hide
 Creators:
Nierhaus, Till1, 2, 3, Author              
Forschack, Norman2, 4, Author              
Piper, Sophie K.1, Author
Holtze, Susanne1, Author
Krause, Thomas1, 5, Author
Taskin, Birol1, 5, Author
Long, Xiangyu2, Author              
Stelzer, Johannes6, Author              
Margulies, Daniel S.3, 7, Author              
Steinbrink, Jens1, 5, Author
Villringer, Arno1, 2, 3, 5, Author              
Affiliations:
1Berlin Neuroimaging Center, Charité University Medicine Berlin, Germany, ou_persistent22              
2Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
3Berlin School of Mind and Brain, Humboldt University Berlin, Germany, ou_persistent22              
4Institute of Psychology, University of Leipzig, Germany, ou_persistent22              
5Center for Stroke Research, Charité University Medicine Berlin, Germany, ou_persistent22              
6Department Neurophysics, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634550              
7 Max Planck Research Group Neuroanatomy and Connectivity, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_1356546              

Content

show
hide
Free keywords: EEG background rhythms; fMRI; Functional connectivity; Somatosensory evoked potentials; Subthreshold electrical stimulation; Unconscious
 Abstract: Most sensory input to our body is not consciously perceived. Nevertheless, it may reach the cortex and influence our behavior. In this study, we investigated noninvasive neural signatures of unconscious cortical stimulus processing to understand mechanisms, which (1) prevent low-intensity somatosensory stimuli from getting access to conscious experience and which (2) can explain the associated impediment of conscious perception for additional stimuli. Stimulation of digit 2 in humans far below the detection threshold elicited a cortical evoked potential (P1) at 60 ms, but no further somatosensory evoked potential components. No event-related desynchronization was detected; rather, there was a transient synchronization in the alpha frequency range. Using the same stimulation during fMRI, a reduced centrality of contralateral primary somatosensory cortex (SI) was found, which appeared to be mainly driven by reduced functional connectivity to frontoparietal areas. We conclude that after subthreshold stimulation the (excitatory) feedforward sweep of bottom-up processing terminates in SI preventing access to conscious experience. We speculate that this interruption is due to a predominance of inhibitory processing in SI. The increase in alpha activity and the disconnection of SI from frontoparietal areas are likely correlates of an elevated perception threshold and may thus serve as a gating mechanism for the access to conscious experience.

Details

show
hide
Language(s): eng - English
 Dates: 2014-09-112015-02-162015-04-15
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1523/JNEUROSCI.3806-14.2015
PMID: 25878264
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: The Journal of Neuroscience
  Other : J. Neurosci.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Baltimore, MD : The Society
Pages: - Volume / Issue: 35 (15) Sequence Number: - Start / End Page: 5917 - 5925 Identifier: ISSN: 0270-6474
CoNE: /journals/resource/954925502187