English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Neural correlates of impaired emotional face recognition in cerebellar lesions

Adamaszek, M., Kirkby, K. C., D'Agata, F., Olbrich, S., Langner, S., Steele, C., et al. (2015). Neural correlates of impaired emotional face recognition in cerebellar lesions. Brain Research, 1613, 1-12. doi:10.1016/j.brainres.2015.01.027.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0026-C59A-A Version Permalink: http://hdl.handle.net/21.11116/0000-0003-7BF0-4
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Adamaszek, Michael1, 2, Author
Kirkby, Kenneth C.3, Author
D'Agata, Fedrico4, Author
Olbrich, Sebastian5, Author
Langner, Sönke6, Author
Steele, Christopher7, Author              
Sehm, Bernhard7, Author              
Busse, Stefan8, Author
Kessler, Christof2, Author
Hamm, Alfons9, Author
Affiliations:
1Department of Neurological Rehabilitation, Bavaria Hospital, Kreischa, Germany, ou_persistent22              
2Department of Neurology, Ernst Moritz Arndt University of Greifswald, Germany, ou_persistent22              
3Department of Psychiatry, School of Medicine, University of Tasmania, Hobart, Australia, ou_persistent22              
4Department of Neuroscience, San Giovanni Battista University Hospital, Turin, Italy, ou_persistent22              
5Department of Psychiatry, University of Leipzig, Germany, ou_persistent22              
6Department of Neuroradiology, Ernst Moritz Arndt University of Greifswald, Germany, ou_persistent22              
7Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
8Department of Psychiatry, Otto von Guericke University Magdeburg, Germany, ou_persistent22              
9Institute of Physiological and Clinical Psychology, Ernst Moritz Arndt University of Greifswald, Germany, ou_persistent22              

Content

show
hide
Free keywords: Cerebellum; Emotional facial expressions; ERP; Prefrontal cortex
 Abstract: Clinical and neuroimaging data indicate a cerebellar contribution to emotional processing, which may account for affective-behavioral disturbances in patients with cerebellar lesions. We studied the neurophysiology of cerebellar involvement in recognition of emotional facial expression. Participants comprised eight patients with discrete ischemic cerebellar lesions and eight control patients without any cerebrovascular stroke. Event-related potentials (ERP) were used to measure responses to faces from the Karolinska Directed Emotional Faces Database (KDEF), interspersed in a stream of images with salient contents. Images of faces augmented N170 in both groups, but increased late positive potential (LPP) only in control patients without brain lesions. Dipole anaylsis revealed altered activation patterns for negative emotions in patients with cerebellar lesions, including activation of the left inferior prefrontal area to images of faces showing fear, contralateral to controls. Correlation analysis indicated that lesions of cerebellar area Crus I contribute to ERP deviations. Overall, our results implicate the cerebellum in integrating emotional information at different higher order stages, suggesting distinct cerebellar contributions to the proposed large-scale cerebral network of emotional face recognition.

Details

show
hide
Language(s): eng - English
 Dates: 2015-01-172015-04-232015-07-10
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.brainres.2015.01.027
PMID: 25912431
Other: Epub 2015
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Brain Research
  Other : Brain Res.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Amsterdam : Elsevier
Pages: - Volume / Issue: 1613 Sequence Number: - Start / End Page: 1 - 12 Identifier: ISSN: 0006-8993
CoNE: https://pure.mpg.de/cone/journals/resource/954926250616