Frequent and focal FGFR1 amplification associates with therapeutically 
tractable FGFR1 dependency in squamous cell lung cancer

Weiss, Jonathan; Sos, Martin L.; Seidel, Danila; Peifer, Martin; Zander, Thomas; Heuckmann, Johannes M.; Ullrich, Roland T.; Menon, Roopika; Maier, Sebastian; Soltermann, Alex; Moch, Holger; Wagener, Patrick; Fischer, Florian; Heynck, Stefanie; Koker, Mirjam; Schöttle, Jakob; Leenders, Frauke; Gabler, Franziska; Dabow, Ines; Querings, Silvia; Heukamp, Lukas C.; Balke-Want, Hyatt; Ansén, Sascha; Rauh, Daniel; Baessmann, Ingelore; Altmüller, Janine; Wainer, Zoe; Conron, Matthew; Wright, Gavin; Russell, Prudence; Solomon, Ben; Brambilla, Elisabeth; Brambilla, Christian; Lorimier, Philippe; Sollberg, Steinar; Brustugun, Odd Terje; Engel-Riedel, Walburga; Ludwig, Corinna; Petersen, Iver; Sänger, Jörg; Clement, Joachim; Groen, Harry; Timens, Wim; Sietsma, Hannie; Thunnissen, Erik; Smit, Egbert; Heidemann, Danielle; Cappuzzo, Frederico; Ligorio, Claudia; Damiani, Stefania; Hallek, Michael; Beroukhim, Rameen; Pao, William; Klebl, Bert; Baumann, Matthias; Buettner, Reinhard; Ernestus, Karen; Stoelben, Erich; Wolf, Jürgen; Nürnberg, Peter; Perner, Sven; Thomas, Roman K.

doi:10.1126/scitranslmed.3001451

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Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer

Weiss, J., Sos, M. L., Seidel, D., Peifer, M., Zander, T., Heuckmann, J. M., et al. (2010). Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer. Science Translational Medicine, 2(62), 62ra93-62ra93. doi:10.1126/scitranslmed.3001451.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0026-D4E2-7 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0026-D4E3-5

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Creators:
Weiss, Jonathan¹, Author
Sos, Martin L.¹, Author
Seidel, Danila¹, Author
Peifer, Martin¹, Author
Zander, Thomas², Author
Heuckmann, Johannes M.¹, Author
Ullrich, Roland T.², Author
Menon, Roopika³, Author
Maier, Sebastian³, Author
Soltermann, Alex³, Author
Moch, Holger³, Author
Wagener, Patrick³, Author
Fischer, Florian¹, Author
Heynck, Stefanie¹, Author
Koker, Mirjam¹, Author
Schöttle, Jakob², Author
Leenders, Frauke⁴, Author
Gabler, Franziska¹, Author
Dabow, Ines³, Author
Querings, Silvia¹, Author
Heukamp, Lukas C.³, AuthorBalke-Want, Hyatt¹, Author         Ansén, Sascha³, AuthorRauh, Daniel³, AuthorBaessmann, Ingelore³, AuthorAltmüller, Janine³, AuthorWainer, Zoe³, AuthorConron, Matthew³, AuthorWright, Gavin³, AuthorRussell, Prudence³, AuthorSolomon, Ben³, AuthorBrambilla, Elisabeth³, AuthorBrambilla, Christian³, AuthorLorimier, Philippe³, AuthorSollberg, Steinar³, AuthorBrustugun, Odd Terje³, AuthorEngel-Riedel, Walburga³, AuthorLudwig, Corinna³, AuthorPetersen, Iver³, AuthorSänger, Jörg³, AuthorClement, Joachim³, AuthorGroen, Harry³, AuthorTimens, Wim³, AuthorSietsma, Hannie³, AuthorThunnissen, Erik³, AuthorSmit, Egbert³, AuthorHeidemann, Danielle³, AuthorCappuzzo, Frederico³, AuthorLigorio, Claudia³, AuthorDamiani, Stefania³, AuthorHallek, Michael³, AuthorBeroukhim, Rameen³, AuthorPao, William³, AuthorKlebl, Bert³, AuthorBaumann, Matthias³, AuthorBuettner, Reinhard³, AuthorErnestus, Karen³, AuthorStoelben, Erich³, AuthorWolf, Jürgen³, AuthorNürnberg, Peter³, AuthorPerner, Sven³, AuthorThomas, Roman K.¹, Author          more..

Affiliations:
1Funktionelle Krebsgenomforschung, Junior Research Groups, Max-Planck-Institut für neurologische Forschung, Managing Director: D. Yves von Cramon, Max Planck Institute for Metabolism Research, Managing Director: Jens Brüning, Max Planck Society, ou_2149656
2Klinisches PET, Neurologische Abteilung, Max-Planck-Institut für neurologische Forschung, Managing Director: D. Yves von Cramon, Max Planck Institute for Metabolism Research, Managing Director: Jens Brüning, Max Planck Society, ou_2149663
31. Laboratory of Translational Cancer Genomics, Center of Integrated Oncology Köln-Bonn, University of Cologne, 50924 Cologne, Germany 2. Department I of Internal Medicine, Center of Integrated Oncology Köln-Bonn, University of Cologne, 50924 Cologne, Germany 3. Institute of Pathology, Comprehensive Cancer Center, University Hospital Tübingen, 72076 Tübingen, Germany 4. Institute for Surgical Pathology, University Hospital Zurich, 8091 Zurich, Switzerland 5. Department of Surgery, Weill Medical College, Cornell University, New York, NY 10065, United States 6. Institute of Pathology, University of Bonn, 53123 Bonn, Germany 7. Chemical Genomics Center, Max Planck Society, 44227 Dortmund, Germany 8. Cologne Center for Genomics, Institute for Genetics, University of Cologne, 50931 Cologne, Germany 9. Department of Surgical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC 3002, Australia 10. Department of Pathology, St. Vincent's Hospital, Melbourne, VIC 3065, Australia 11. Department of Haematology and Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC 3002, Australia 12. Department of Pathology, Université Joseph Fourier, 38041 Grenoble, France 13. Institut Albert Bonniot INSERM U823, Université Joseph Fourier, 38042 Grenoble, France 14. Department of Thoracic Surgery, Rikshospitalet, Oslo University Hospital, 0027 Oslo, Norway 15. Department of Radiation Biology, Norwegian Radium Hospital, N-0310 Oslo, Norway 16. Department of Oncology, Radiumhospitalet, Oslo University Hospital, N-0310 Oslo, Norway 17. Thoracic Surgery, Lungenklinik Merheim, Kliniken der Stadt Köln gGmbH, 51109 Cologne, Germany 18. Institute of Pathology, Jena University Hospital, Friedrich-Schiller-University, 07743 Jena, Germany 19. Institute for Pathology Bad Berka, 99438 Bad Berka, Germany 20. Department for Internal Medicine II, University Clinic Jena, Friedrich-Schiller University, 07740 Jena, Germany 21. Department of Pulmonary Diseases, University Medical Centre Groningen, 9713 GZ Groningen, Netherlands 22. Department of Pathology, University Medical Centre Groningen, 9713 GZ Groningen, Netherlands 23. Department of Pathology, VU University Medical Center Amsterdam, 1007 MB Amsterdam, Netherlands 24. Department of Pulmonary Diseases, VU University Medical Center Amsterdam, 1007 MB Amsterdam, Netherlands 25. Department of Medical Oncology, Ospedale Civile, 57100 Livorno, Italy 26. Department of Haematology and Oncologic Science, University Hospital Bologna, 40138 Bologna, Italy 27. Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases, University of Cologne, 50931 Cologne, Germany 28. Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, United States 29. Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, United States 30. Department of Medicine, Harvard Medical School, Boston, MA 02115, United States 31. Cancer Program, Broad Institute, Cambridge, MA 02115, United States 32. Vanderbilt-Ingram Cancer Center, Nashville, TN 37212, United States 33. Lead Discovery Center GmbH, 44227 Dortmund, Germany 34. Department of Pathology, Hospital Merheim, Kliniken der Stadt Köln gGmbH, 51109 Cologne, Germany, ou_persistent22
4Max Planck Society, ou_persistent13

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Language(s): eng - English

Dates: Date issued: 2010

Publication Status: Issued

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Rev. Type: Peer

Identifiers: eDoc: 572952
DOI: 10.1126/scitranslmed.3001451

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Title: Science Translational Medicine

Source Genre: Journal

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Pages: - Volume / Issue: 2 (62) Sequence Number: - Start / End Page: 62ra93 - 62ra93 Identifier: ISSN: 19466234