Insulin receptor signaling mediates APP processing and β-amyloid accumulation 
without altering survival in a transgenic mouse model of Alzheimer's disease

Stöhr, Oliver; Schilbach, Katharina; Moll, Lorna; Hettich, Moritz M.; Freude, Susanna; Wunderlich, Frank Thomas; Ernst, Marianne; Zemva, Johanna; Brüning, Jens Claus; Krone, Wilhelm; Udelhoven, Michael; Schubert, Markus

doi:10.1007/s11357-011-9333-2

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Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease

Stöhr, O., Schilbach, K., Moll, L., Hettich, M. M., Freude, S., Wunderlich, F. T., et al. (2013). Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease. AGE, 35(1), 83-101. doi:10.1007/s11357-011-9333-2.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0026-D5FB-9 Version Permalink: https://hdl.handle.net/21.11116/0000-000D-14A7-0

Genre: Journal Article

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Creators:
Stöhr, Oliver¹, Author
Schilbach, Katharina¹, Author
Moll, Lorna¹, Author
Hettich, Moritz M.¹, Author
Freude, Susanna¹, Author
Wunderlich, Frank Thomas², Author
Ernst, Marianne¹, Author
Zemva, Johanna¹, Author
Brüning, Jens Claus³, Author
Krone, Wilhelm¹, Author
Udelhoven, Michael¹, Author
Schubert, Markus¹, Author

Affiliations:
1a Center for Endocrinology, Diabetes and Preventive Medicine (CEDP), Center for Molecular Medicine Col, University of Cologne, Kerpener Str 62, Cologne, 50931, Germany b Cologne excellence cluster in Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany c Molecular and Cellular Cognition Lab, German Centre for Neurodegenerative Diseases (DZNE), Bonn, 53175, Germany d Department of Mouse Genetics and Metabolism, Institute for Genetics University of Cologne, Zülpicher Strasse 47, Cologne, 50674, Germany e Center for Endocrinology, Diabetes and Preventive Medicine, University of Cologne, CMMC building 66, 5.012, Robert-Koch-Str. 21, Cologne, 50931, Germany, ou_persistent22
2Wunderlich – Obesity and Cancer, Department Brüning, Max Planck Institute for Metabolism Research, Max Planck Society, ou_2149645
3Brüning – Neuronal Control of Metabolism, Department Brüning, Max Planck Institute for Metabolism Research, Max Planck Society, ou_2149644

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Language(s): eng - English

Dates: Date issued: 2013

Publication Status: Issued

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Rev. Type: Peer

Identifiers: eDoc: 573598
DOI: 10.1007/s11357-011-9333-2

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Title: AGE

Source Genre: Journal

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Pages: - Volume / Issue: 35 (1) Sequence Number: - Start / End Page: 83 - 101 Identifier: ISSN: 01619152