Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain 
and glucose intolerance

Turpin, Sarah M.; Nicholls, Hayley T.; Willmes, Diana M.; Mourier, Arnaud; Brodesser, Susanne; Wunderlich, Claudia M.; Mauer, Jan; Xu, Elaine; Hammerschmidt, Philipp; Brönneke, Hella S.; Trifunovic, Aleksandra; LoSasso, Giuseppe; Wunderlich, Frank Thomas; Kornfeld, Jan-Wilhelm; Blüher, Matthias; Krönke, Martin; Brüning, Jens Claus

doi:10.1016/j.cmet.2014.08.002

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Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance

Turpin, S. M., Nicholls, H. T., Willmes, D. M., Mourier, A., Brodesser, S., Wunderlich, C. M., et al. (2014). Obesity-induced CerS6-dependent C16:0 ceramide production promotes weight gain and glucose intolerance. Cell Metabolism, 20(4), 678-686. doi:10.1016/j.cmet.2014.08.002.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0026-D7BB-D Version Permalink: https://hdl.handle.net/21.11116/0000-000D-12CD-8

Genre: Journal Article

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Creators:
Turpin, Sarah M.¹, Author
Nicholls, Hayley T.¹, Author
Willmes, Diana M.¹, Author
Mourier, Arnaud², Author
Brodesser, Susanne², Author
Wunderlich, Claudia M.³, Author
Mauer, Jan¹, Author
Xu, Elaine¹, Author
Hammerschmidt, Philipp¹, Author
Brönneke, Hella S.⁴, Author
Trifunovic, Aleksandra², Author
LoSasso, Giuseppe², Author
Wunderlich, Frank Thomas⁵, Author
Kornfeld, Jan-Wilhelm⁶, Author
Blüher, Matthias², Author
Krönke, Martin², Author
Brüning, Jens Claus⁷, Author

Affiliations:
1Neuronal Control of Metabolism, Department Jens Brüning, Max Planck Institute for Metabolism Research, Managing Director: Jens Brüning, Max Planck Society, ou_2149644
2a CECADCologne, North Rhine-Westphalia, Germany b Max Planck Institute for the Biology of AgingCologne, North Rhine-Westphalia, Germany c Laboratory of Integrative and Systems Physiology, School of Life Sciences, École Polytechnique FédéraleLausanne, Switzerland d Department of Medicine, University of LeipzigLeipzig, Saxony, Germany e Institute for Medical Microbiology, University Hospital CologneCologne, North Rhine-Westphalia, Germany f Center for Endocrinology, Diabetes and Preventive Medicine (CEDP), University Hospital CologneCologne, North Rhine-Westphalia, Germany, ou_persistent22
3Obesity and Cancer, Department Jens Brüning, Max Planck Institute for Metabolism Research, Managing Director: Jens Brüning, Max Planck Society, ou_2149645
4Preclinical Phenotyping, Scientific Services and Development, Max Planck Institute for Metabolism Research, Managing Director: Jens Brüning, Max Planck Society, ou_2149671
5Wunderlich – Obesity and Cancer, Department Brüning, Max Planck Institute for Metabolism Research, Max Planck Society, ou_2149645
6Noncoding RNAs and Energy Homeostatis, MPG Research Groups, Max Planck Institute for Metabolism Research, Managing Director: Jens Brüning, Max Planck Society, ou_2149651
7Brüning – Neuronal Control of Metabolism, Department Brüning, Max Planck Institute for Metabolism Research, Max Planck Society, ou_2149644

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Language(s): eng - English

Dates: Date issued: 2014

Publication Status: Issued

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Rev. Type: Peer

Identifiers: eDoc: 696022
DOI: 10.1016/j.cmet.2014.08.002

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Title: Cell Metabolism

Source Genre: Journal

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Pages: - Volume / Issue: 20 (4) Sequence Number: - Start / End Page: 678 - 686 Identifier: ISSN: 15504131