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  Obesity-induced over expression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism

Jordan, S. D., Krüger, M., Willmes, D. M., Redemann, N., Wunderlich, F. T., Brönneke, H. S., et al. (2011). Obesity-induced over expression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. Nature Cell Biology, 13(4), 434-446. doi:10.1038/ncb2211.

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 Creators:
Jordan, Sabine D.1, Author
Krüger, Markus1, Author
Willmes, Diana M.2, Author           
Redemann, Nora1, Author
Wunderlich, F. Thomas3, Author           
Brönneke, Hella S.4, Author           
Merkwirth, Carsten1, Author
Kashkar, Hamidi1, Author
Olkkonen, Vesa M.1, Author
Böttger, Thomas1, Author
Braun, Thomas1, Author
Seibler, Jost1, Author
Brüning, Jens C.2, Author           
Affiliations:
11. Univ Cologne, Dept Mouse Genet & Metab, Inst Genet, Cologne Excellence Cluster Cellular Stress Respon, D-50674 Cologne, Germany 2. Univ Cologne, CMMC, D-50674 Cologne, Germany 3. Univ Hosp Cologne, Max Planck Inst Neurol Res, Ctr Endocrinol Diabet & Prevent Med CEDP, D-50674 Cologne, Germany 4. Max Planck Inst Heart & Lung Res, D-61231 Bad Nauheim, Germany 5. Cologne Excellence Cluster Cellular Stress Respon, Phenotyping Facil, D-50674 Cologne, Germany 6. Univ Cologne, Inst Med Microbiol Immunol & Hyg, Cologne Excellence Cluster Cellular Stress Respon, D-50674 Cologne, Germany 7. TaconicArtemis Pharmaceut GmbH, D-51063 Cologne, Germany 8. Minerva Fdn, Biomedicum, FI-00290 Helsinki, Finland, ou_persistent22              
2Neuronal Control of Metabolism, Department Jens Brüning, Max Planck Institute for Metabolism Research, Managing Director: Jens Brüning, Max Planck Society, ou_2149644              
3Obesity and Cancer, Department Jens Brüning, Max Planck Institute for Metabolism Research, Managing Director: Jens Brüning, Max Planck Society, ou_2149645              
4Preclinical Phenotyping, Scientific Services and Development, Max Planck Institute for Metabolism Research, Managing Director: Jens Brüning, Max Planck Society, ou_2149671              

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 Abstract: © 2011 Nature Publishing Group

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Language(s): eng - English
 Dates: 2011
 Publication Status: Published in print
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 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 589743
DOI: 10.1038/ncb2211
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Title: Nature Cell Biology
Source Genre: Journal
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Pages: - Volume / Issue: 13 (4) Sequence Number: - Start / End Page: 434 - 446 Identifier: ISSN: 1465-7392