Obesity-induced over expression of miRNA-143 inhibits insulin-stimulated AKT 
activation and impairs glucose metabolism

Jordan, Sabine D.; Krüger, Markus; Willmes, Diana M.; Redemann, Nora; Wunderlich, F. Thomas; Brönneke, Hella S.; Merkwirth, Carsten; Kashkar, Hamidi; Olkkonen, Vesa M.; Böttger, Thomas; Braun, Thomas; Seibler, Jost; Brüning, Jens C.

doi:10.1038/ncb2211

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Obesity-induced over expression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism

Jordan, S. D., Krüger, M., Willmes, D. M., Redemann, N., Wunderlich, F. T., Brönneke, H. S., et al. (2011). Obesity-induced over expression of miRNA-143 inhibits insulin-stimulated AKT activation and impairs glucose metabolism. Nature Cell Biology, 13(4), 434-446. doi:10.1038/ncb2211.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0026-D7BF-5 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0026-D7C0-0

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Jordan, Sabine D.¹, Author
Krüger, Markus¹, Author
Willmes, Diana M.², Author
Redemann, Nora¹, Author
Wunderlich, F. Thomas³, Author
Brönneke, Hella S.⁴, Author
Merkwirth, Carsten¹, Author
Kashkar, Hamidi¹, Author
Olkkonen, Vesa M.¹, Author
Böttger, Thomas¹, Author
Braun, Thomas¹, Author
Seibler, Jost¹, Author
Brüning, Jens C.², Author

Affiliations:
11. Univ Cologne, Dept Mouse Genet & Metab, Inst Genet, Cologne Excellence Cluster Cellular Stress Respon, D-50674 Cologne, Germany 2. Univ Cologne, CMMC, D-50674 Cologne, Germany 3. Univ Hosp Cologne, Max Planck Inst Neurol Res, Ctr Endocrinol Diabet & Prevent Med CEDP, D-50674 Cologne, Germany 4. Max Planck Inst Heart & Lung Res, D-61231 Bad Nauheim, Germany 5. Cologne Excellence Cluster Cellular Stress Respon, Phenotyping Facil, D-50674 Cologne, Germany 6. Univ Cologne, Inst Med Microbiol Immunol & Hyg, Cologne Excellence Cluster Cellular Stress Respon, D-50674 Cologne, Germany 7. TaconicArtemis Pharmaceut GmbH, D-51063 Cologne, Germany 8. Minerva Fdn, Biomedicum, FI-00290 Helsinki, Finland, ou_persistent22
2Neuronal Control of Metabolism, Department Jens Brüning, Max Planck Institute for Metabolism Research, Managing Director: Jens Brüning, Max Planck Society, ou_2149644
3Obesity and Cancer, Department Jens Brüning, Max Planck Institute for Metabolism Research, Managing Director: Jens Brüning, Max Planck Society, ou_2149645
4Preclinical Phenotyping, Scientific Services and Development, Max Planck Institute for Metabolism Research, Managing Director: Jens Brüning, Max Planck Society, ou_2149671

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Language(s): eng - English

Dates: Date issued: 2011

Publication Status: Issued

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Rev. Type: Peer

Identifiers: eDoc: 589743
DOI: 10.1038/ncb2211

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Title: Nature Cell Biology

Source Genre: Journal

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Pages: - Volume / Issue: 13 (4) Sequence Number: - Start / End Page: 434 - 446 Identifier: ISSN: 1465-7392