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  W(h)ither human cardiac and body magnetic resonance at ultrahigh fields? Technical advances, practical considerations, applications, and clinical opportunities.

Niendorf, T., Paul, K., Oezerdem, C., Graessl, A., Klix, S., Huelnhagen, T., et al. (2016). W(h)ither human cardiac and body magnetic resonance at ultrahigh fields? Technical advances, practical considerations, applications, and clinical opportunities. NMR in Biomedicine, 29(9), 1173-1197. doi:10.1002/nbm.3268.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0026-CE50-C Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002C-7FE5-B
Genre: Journal Article

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 Creators:
Niendorf, T., Author
Paul, K., Author
Oezerdem, C., Author
Graessl, A., Author
Klix, S., Author
Huelnhagen, T., Author
Hezel, F., Author
Rieger, J., Author
Waiczies, H., Author
Oberacker, E., Author
Frahm, J.1, Author              
Nagel, A., Author
Winter, L., Author
Affiliations:
1Biomedical NMR Research GmbH, MPI for biophysical chemistry, Max Planck Society, ou_578634              

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Free keywords: magnetic resonance; MRI; ultrahigh field; cardiovascular imaging; body imaging; heteronuclear MR; MR technology; RF coils
 Abstract: The objective of this study was to document and review advances and groundbreaking progress in cardiac and body MR at ultrahigh fields (UHF, B0 ≥ 7.0 T) with the goal to attract talent, clinical adopters, collaborations and resources to the biomedical and diagnostic imaging communities. This review surveys traits, advantages and challenges of cardiac and body MR at 7.0 T. The considerations run the gamut from technical advances to clinical opportunities. Key concepts, emerging technologies, practical considerations, frontier applications and future directions of UHF body and cardiac MR are provided. Examples of UHF cardiac and body imaging strategies are demonstrated. Their added value over the kindred counterparts at lower fields is explored along with an outline of research promises. The achievements of cardiac and body UHF-MR are powerful motivators and enablers, since extra speed, signal and imaging capabilities may be invested to overcome the fundamental constraints that continue to hamper traditional cardiac and body MR applications. If practical obstacles, concomitant physics effects and technical impediments can be overcome in equal measure, sophisticated cardiac and body UHF-MR will help to open the door to new MRI and MRS approaches for basic research and clinical science, with the lessons learned at 7.0 T being transferred into broad clinical use including diagnostics and therapy guiding at lower fields

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Language(s): eng - English
 Dates: 2015-02-232016-09
 Publication Status: Published in print
 Pages: -
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 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1002/nbm.3268
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Title: NMR in Biomedicine
Source Genre: Journal
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Pages: - Volume / Issue: 29 (9) Sequence Number: - Start / End Page: 1173 - 1197 Identifier: -