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  Polysaccharide antigen-glycolipid conjugate vaccines

Seeberger, P. H., Stallforth, P., De Libero, G., & Cavallari, M.(2013). Polysaccharide antigen-glycolipid conjugate vaccines.

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2156805.pdf (Publisher version), 4MB
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 Creators:
Seeberger, Peter H.1, Author           
Stallforth, Pierre2, Author           
De Libero, Gennaro, Author
Cavallari, Marco, Author
Affiliations:
1Peter H. Seeberger - Vaccine Development, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863308              
2Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863286              

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 Abstract: The present invention relates to the field of synthesizing and biologically evaluating of a novel class of carbohydratebased
vaccines. The new vaccines consist of a multi- modular structure which allows applying the vaccine to a whole variety of
pathogenes. This method allows preparing vaccines against all pathogens expressing immunogenic carbohydrate antigens. As conjugation
of antigenic carbohydrates to proteins is not required the conjugate vaccine is particularly heat stable. No refrigeration is required,
a major drawback of protein-based vaccines.

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 Dates: 2012-03-192013-09-26
 Publication Status: Published online
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 Identifiers: Patent Application Nr.: PCT/EP2012/054848
Patent Publication Nr.: WO2013139803
Patent Nr.: EP2827899
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