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  Assessment of T1, T1ρ, and T2 values of the ulnocarpal disc in healthy subjects at 3 tesla

Rauscher, I., Bender, B., Grözinger, G., Luz, O., Pohmann, R., Erb, M., et al. (2014). Assessment of T1, T1ρ, and T2 values of the ulnocarpal disc in healthy subjects at 3 tesla. Magnetic Resonance Imaging, 32(9), 1085-1090. doi:10.1016/j.mri.2014.05.010.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0027-7F91-D Version Permalink: http://hdl.handle.net/21.11116/0000-0001-2229-B
Genre: Journal Article

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Rauscher, I, Author
Bender, B, Author
Grözinger, G, Author
Luz, O, Author
Pohmann, R1, 2, Author              
Erb, M, Author              
Schick, F, Author
Martirosian, P, Author
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: Objective The purpose of this study was to implement clinically feasible imaging techniques for determination of T1, T1⁽˚ho⁾, and T2 values of the ulnocarpal disc and to assess those values in a cohort of asymptomatic subjects at 3 Tesla. Resulting values were compared between different age groups, since former histological findings of the ulnocarpal disc indicated frequent early degenerative changes of this tissue starting in the third decade of life, even in asymptomatic subjects. Materials and Methods Twenty-seven healthy subjects were included in this study. T1 measurements were performed using 3D spoiled gradient-echo (GRE) sequence with variable flip angle. Series of T1⁽˚ho⁾ and T2-weighted images were acquired by a 3D GRE sequence after suitable magnetization preparation. T1,T1⁽˚ho⁾, and T2 maps of the ulnocarpal disc were calculated pixel-wise. Representative mean values from extended regions were analysed. Results Mean T1 values of the ulnocarpal disc ranged from 722 ms in a 39 year-old subject to 1264 ms in a 65 year-old subject, T1⁽˚ho⁾ ranged from 9.2 ms (26 year-old subject) to 25.9 ms (65 year-old subject). Calculated T2 values showed a large range from 4.1 ms to 22.3 ms. T1⁽˚ho⁾ and T1 values tended to increase with age (p < 0.05), whereas T2 did not. Conclusions MR relaxometry of the ulnocarpal disc is feasible, and T1,T1⁽˚ho⁾, and T2 values show modest variance in asymptomatic subjects. The potential of relaxation mapping to reveal relevant structural changes in patients has to be investigated in further studies.

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 Dates: 2014-11
 Publication Status: Published in print
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 Identifiers: DOI: 10.1016/j.mri.2014.05.010
BibTex Citekey: RauscherBGLPESM2014
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Title: Magnetic Resonance Imaging
Source Genre: Journal
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Pages: - Volume / Issue: 32 (9) Sequence Number: - Start / End Page: 1085 - 1090 Identifier: -