English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  ProFit revisited

Fuchs, A., Boesiger, P., Schulte, R., & Henning, A. (2014). ProFit revisited. Magnetic Resonance in Medicine, 71(2), 458-468. doi:10.1002/mrm.24703.

Item is

Files

show Files

Locators

show
hide
Description:
-
OA-Status:

Creators

show
hide
 Creators:
Fuchs, A, Author
Boesiger, P, Author
Schulte, RF, Author
Henning, A1, Author           
Affiliations:
1Department of Information Technology and Electrical Engineering, Institute for Biomedical Engineering, ETH & University Zurich, ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: Purpose An enhanced version of the ProFit fitting tool was developed and validated to improve the quantification of two-dimensional JRPESS spectroscopic data. Methods The proposed enhancements were achieved by flexible organization of prior knowledge, configurations for different situations, the inclusion of measured macromolecular baseline contribution, additional baseline splines and a model-free lineshape based on self-deconvolution. The new software was tested and tuned on simulated data and subsequently applied to in vivo intrasubject and intersubject data. Results Fit results of simulated and acquired spectra show good overall quality suggesting the potential reliable detection of up to 18 metabolites on a 3T system yielding Cramer-Lower-Bounds below 20%. Conclusion The proposed enhanced version of ProFit together with two-dimensional J-resolved spectroscopy offers the opportunity to reliably detect a wide selection of important brain metabolites on 3T.

Details

show
hide
Language(s):
 Dates: 2014-02
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.1002/mrm.24703
BibTex Citekey: FuchsSBH2013
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Magnetic Resonance in Medicine
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 71 (2) Sequence Number: - Start / End Page: 458 - 468 Identifier: -