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  SnapShot: Spliceosome dynamics I.

Wahl, M. C., & Lührmann, R. (2015). SnapShot: Spliceosome dynamics I. Cell, 161(6), 1474-1474.e1. doi:10.1016/j.cell.2015.05.050.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0027-835F-6 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-002A-600A-E
Genre: Journal Article

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2161199.pdf (Publisher version), 991KB
 
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 Creators:
Wahl, M. C., Author
Lührmann, R.1, Author              
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1Department of Cellular Biochemistry, MPI for biophysical chemistry, Max Planck Society, ou_578576              

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 Abstract: Spliceosomes are multi-megadalton RNA-protein molecular machines that carry out pre-mRNA splicing, that is, the removal of non-coding intervening sequences (introns) from eukaryotic pre-mRNAs and the ligation of neighboring coding regions (exons) to produce mature mRNA for protein biosynthesis on the ribosome. They are the prototypes of dynamic molecular machines, assembling de novo for each splicing event by the stepwise recruitment of subunits on a substrate.

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Language(s): eng - English
 Dates: 2015-06-04
 Publication Status: Published online
 Pages: -
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 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1016/j.cell.2015.05.050
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Title: Cell
Source Genre: Journal
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Publ. Info: -
Pages: 2 Volume / Issue: 161 (6) Sequence Number: - Start / End Page: 1474 - 1474.e1 Identifier: -