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  Imaging and nanomedicine for diagnosis and therapy in the central nervous system: Report of the eleventh annual blood-brain barrier disruption consortium meeting.

Muldoon, L., Tratnyek, P., Jacobs, P. M., Doolittle, N. D., Christoforidis, G. A., Frank, J. A., et al. (2006). Imaging and nanomedicine for diagnosis and therapy in the central nervous system: Report of the eleventh annual blood-brain barrier disruption consortium meeting. American Journal of Neuroradiology, 27, 715-721.

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 Creators:
Muldoon, L.L., Author
Tratnyek, P.G., Author
Jacobs, P. M., Author
Doolittle, N. D., Author
Christoforidis, G. A., Author
Frank, J. A., Author
Lindau, M.1, Author              
Lockman, P. R., Author
Manninger, S. P., Author
Qiang, Q., Author
Spence, A. M., Author
Stupp, S. I., Author
Zhang, M., Author
Neuwelt, E. A., Author
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1Research Group of Nanoscale Cell Biology, MPI for Biophysical Chemistry, Max Planck Society, ou_1832294              

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 Abstract: The blood-brain barrier (BBB) presents a major obstacle to the treatment of malignant brain tumors and other central nervous system (CNS) diseases. The Eleventh Annual Blood-Brain Barrier Disruption Consortium Meeting was convened to discuss recent advances and future directions in imaging and nanomedicine. Two sessions, one on Cell and Molecular Imaging in the CNS and another on Nanotechnology, Nanobiology, and Nanomedicine, were held March 17-18, 2005, in Portland, Ore. CNS imaging presentations targeted differentiating tumor, neural lesions, and necrosis from healthy brain tissue; methods of delivery of imaging agents across the BBB; and new iron oxide-based nanoparticle contrast agents for MR imaging. Nanobiology presentations covered the development of new nanotechnology and its use in imaging, diagnosis, and therapy in the CNS. Discussions at this meeting stressed the role of biotechnology in the convergence of CNS imaging and nanomedicine and are summarized in this article.

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Language(s): eng - English
 Dates: 2006-03
 Publication Status: Published in print
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Title: American Journal of Neuroradiology
Source Genre: Journal
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Pages: - Volume / Issue: 27 Sequence Number: - Start / End Page: 715 - 721 Identifier: -