非表示:
キーワード:
Transgender, Estradiol, Testosterone, Neurotrophin, Gender identity disorder, Gender dysphoria
要旨:
Serum levels of brain-derived neurotrophic factor (BDNF) are reduced in
male-to-female transsexual persons (MtF) compared to male controls. It
was hypothesized before that this might reflect either an involvement of
BDNF in a biomechanism of transsexualism or to be the result of
persistent social stress due to the condition. Here, we demonstrate that
12 month of cross-sex hormone treatment reduces serum BDNF levels in
male-to-female transsexual persons independent of anthropometric
measures. Participants were acquired through the European Network for
the Investigation of Gender Incongruence (ENIGI). Reduced serum BDNF in
MtF thus seems to be a result of hormonal treatment rather than a
consequence or risk factor of transsexualism. (C) 2014 Elsevier B.V. and
ECNP. All rights reserved.
