非表示:
キーワード:
REM, Sleep, Memory, Learning, Amygdala, Hippocampus, mPFC
要旨:
Over the years, rapid eye movement (REM) sleep has been associated with
general memory consolidation, specific consolidation of perceptual,
procedural, emotional and fear memories, brain maturation and
preparation of waking consciousness. More recently, some of these
associations (e.g., general and procedural memory consolidation) have
been shown to be unlikely, while others (e.g., brain maturation and
consciousness) remain inconclusive. In this review, we argue that both
behavioral and neurophysiological evidence supports a role of REM sleep
for amygdala-related memory processing: the amygdala-hippocampus-medial
prefrontal cortex network involved in emotional processing, fear memory
and valence consolidation shows strongest activity during REM sleep, in
contrast to the hippocampus-medial prefrontal cortex only network which
is more active during non-REM sleep. However, more research is needed to
fully understand the mechanisms. (C) 2015 Elsevier Inc. All rights
reserved.
