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Free keywords:
chemotaxis;oscillations; cell shape; electric cell–substrate impedance sensing; cAMP
Abstract:
Time-resolved analysis employing electric cell–substrate impedance sensing reveals periodic impedance changes of small ensembles of Dictyostelium discoideum amoebae oscillating synchronously upon deprivation of food. Impedance changes are attributed to periodic alter ations of cell shape and cell–substrate distance. Ultrasmall electrodes allow the detection of single cell traces.