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  Describing the dynamics of processes consisting simultaneously of Poissonian and non-Poissonian kinetics

Eule, S., & Friedrich, R. (n.d.). Describing the dynamics of processes consisting simultaneously of Poissonian and non-Poissonian kinetics. Physical Review E, 87: 032162. doi:10.1103/PhysRevE.87.032162.

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Eule, Stephan1, Autor           
Friedrich, Rudolf, Autor
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1Department of Nonlinear Dynamics, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society, ou_2063286              

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 Zusammenfassung: Dynamical processes exhibiting non-Poissonian kinetics with nonexponential waiting times are frequently encountered in nature. Examples are biochemical processes like gene transcription which are known to involve multiple intermediate steps. However, often a second process, obeying Poissonian statistics, affects the first one simultaneously, such as the degradation of mRNA in the above example. The aim of the present article is to provide a concise treatment of such random systems which are affected by regular and non-Poissonian kinetics at the same time. We derive the governing master equation and provide a controlled approximation scheme for this equation. The simplest approximation leads to generalized reaction rate equations. For a simple model of gene transcription we solve the resulting equation and show how the time evolution is influenced significantly by the type of waiting time distribution assumed for the non-Poissonian process.

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Sprache(n): eng - English
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 Ort, Verlag, Ausgabe: -
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 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: eDoc: 673705
DOI: 10.1103/PhysRevE.87.032162
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Titel: Physical Review E
Genre der Quelle: Zeitschrift
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Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 87 Artikelnummer: 032162 Start- / Endseite: - Identifikator: -