English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
 Local TagsRelease HistoryDetailsSummary
  Calcium sensitivity of glutamate release in a calyx-type terminal

Bollmann, J. H., Sakmann, B., & Borst, J. G. G. (2000). Calcium sensitivity of glutamate release in a calyx-type terminal. Science, 289(5481), 953-957. doi:10.1126/science.289.5481.953.

Item is

 

show all hide all

Basic

show hide
Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0028-307D-4 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-0028-3094-E
Genre: Journal Article
Alternative Title : Calcium sensitivity of glutamate release in a calyx-type terminal

Files

show Files
hide Files
:
Science_289_2000_953.pdf (Any fulltext), 247KB
 
File Permalink:
-
Name:
Science_289_2000_953.pdf
Description:
-
OA-Status:
Visibility:
Restricted (Max Planck Institute for Medical Research, MHMF; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Locator:
http://www.sciencemag.org/cgi/reprint/289/5481/953 (Any fulltext)
Description:
-
OA-Status:
Locator:
http://dx.doi.org/10.1126/science.289.5481.953 (Any fulltext)
Description:
-
OA-Status:

Creators

show
hide
 Creators:
Bollmann, Johann H.1, Author           
Sakmann, Bert1, Author           
Borst, J. Gerard G.1, Author           
Affiliations:
1Department of Cell Physiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497701              

Content

show
hide
Free keywords: -
 Abstract: Synaptic efÞcacy critically depends on the presynaptic intracellular calcium concentration ([Ca21]i). We measured the calcium sensitivity of glutamate release in a rat auditory brainstem synapse by laser photolysis of caged calcium. A rise in [Ca21]i to 1 micromolar readily evoked release. An increase to .30 micromolar depleted the releasable vesicle pool in ,0.5 millisecond. A comparison with action potentialÐevoked release suggested that a brief increase of [Ca21]i to ;10 micromolar would be sufÞcient to reproduce the physiological release pattern. Thus, the calcium sensitivity of release at this synapse is high, and the distinction between phasic and delayed release is less pronounced than previously thought.

Details

show
hide
Language(s): eng - English
 Dates: 2000-05-012000-07-012000-08-11
 Publication Status: Issued
 Pages: 5
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 666372
DOI: 10.1126/science.289.5481.953
URI: http://www.ncbi.nlm.nih.gov/pubmed/10937999
URI: http://www.sciencemag.org/content/289/5481/953.full
Other: 4698
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Science
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Washington, D.C. : American Association for the Advancement of Science
Pages: - Volume / Issue: 289 (5481) Sequence Number: - Start / End Page: 953 - 957 Identifier: ISSN: 0036-8075
CoNE: https://pure.mpg.de/cone/journals/resource/991042748276600_1