ausblenden:
Schlagwörter:
circadian clock;clock genes;entrainment;light;mammals;peripheral clocks;SCN
Zusammenfassung:
A network of cellular circadian clocks adapts physiology to the 24-hour day cycle. Traditionally clock entrainment has been conceptualized in a hierarchical scheme with a light-reset SCN pacemaker that subsequently aligns subordinate peripheral clocks. New experiments suggest that resetting of the circadian system occurs in a more “federated” fashion allowing for increased noise resistance and plasticity of circadian timekeeping under complex natural conditions.