English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Mechanical homeostasis of a DOPA-enriched biological coating from mussels in response to metal variation.

Schmitt, C. N. Z., Winter, A., Bertinetti, L., Masic, A., Strauch, P., & Harrington, M. J. (2015). Mechanical homeostasis of a DOPA-enriched biological coating from mussels in response to metal variation. Journal of the Royal Society Interface, 12(110): 20150466. doi:10.1098/rsif.2015.0466.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0028-966D-0 Version Permalink: http://hdl.handle.net/21.11116/0000-0002-79CD-0
Genre: Journal Article

Files

show Files
hide Files
:
2186312.pdf (Publisher version), 695KB
 
File Permalink:
-
Name:
2186312.pdf
Description:
-
Visibility:
Restricted (Max Planck Institute of Colloids and Interfaces, MTKG; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-
:
2186312_supp.doc (Supplementary material), 3MB
Name:
2186312_supp.doc
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/msword / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Schmitt, Clemens N. Z.1, Author              
Winter, Alette, Author
Bertinetti, Luca2, Author              
Masic, Admir2, Author              
Strauch, Peter, Author
Harrington, Matthew J.1, Author              
Affiliations:
1Matthew Harrington, Biomaterialien, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863292              
2Peter Fratzl, Biomaterialien, Max Planck Institute of Colloids and Interfaces, Max Planck Society, ou_1863294              

Content

show
hide
Free keywords: -
 Abstract: Protein–metal coordination interactions were recently found to function as crucial mechanical cross-links in certain biological materials. Mussels, for example, use Fe ions from the local environment coordinated to DOPA-rich proteins to stiffen the protective cuticle of their anchoring byssal attachment threads. Bioavailability of metal ions in ocean habitats varies significantly owing to natural and anthropogenic inputs on both short and geological spatio-temporal scales leading to large variations in byssal thread metal composition; however, it is not clear how or if this affects thread performance. Here, we demonstrate that in natural environments mussels can opportunistically replace Fe ions in the DOPA coordination complex with V and Al. In vitro removal of the native DOPA–metal complexes with ethylenediaminetetraacetic acid and replacement with either Fe or V does not lead to statistically significant changes in cuticle performance, indicating that each metal ion is equally sufficient as a DOPA cross-linking agent, able to account for nearly 85% of the stiffness and hardness of the material. Notably, replacement with Al ions also leads to full recovery of stiffness, but only 82% recovery of hardness. These findings have important implications for the adaptability of this biological material in a dynamically changing and unpredictable habitat.

Details

show
hide
Language(s):
 Dates: 2015-08-262015
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: ISI: 26311314
DOI: 10.1098/rsif.2015.0466
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Journal of the Royal Society Interface
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: London : Royal Society
Pages: - Volume / Issue: 12 (110) Sequence Number: 20150466 Start / End Page: - Identifier: ISSN: 1742-5689