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  TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the SARS-coronavirus spike-protein

Heurich, A., Hofmann-Winkler, H., Gierer, S., Liepold, T., Jahn, O., & Pöhlmann, S. (2014). TMPRSS2 and ADAM17 cleave ACE2 differentially and only proteolysis by TMPRSS2 augments entry driven by the SARS-coronavirus spike-protein. Journal of Virology, 88, 1293-1307. doi:10.1128/JVI.02202-13.

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 Creators:
Heurich, Adeline, Author
Hofmann-Winkler, Heike, Author
Gierer, Stefanie, Author
Liepold, Thomas1, Author           
Jahn, Olaf1, Author           
Pöhlmann, Stefan, Author
Affiliations:
1Proteomics, Wiss. Servicegruppen, Max Planck Institute of Experimental Medicine, Max Planck Society, ou_2173673              

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Free keywords: SARS; ACE2; TMPRSS2; ADAM17; Protease; Entry
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Language(s): eng - English
 Dates: 2014
 Publication Status: Published in print
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 Rev. Type: Peer
 Identifiers: eDoc: 670963
DOI: 10.1128/JVI.02202-13
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Title: Journal of Virology
Source Genre: Journal
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Pages: - Volume / Issue: 88 Sequence Number: - Start / End Page: 1293 - 1307 Identifier: -