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  Olfactory signalling in vertebrates and insects: differences and commonalities

Kaupp, U. B. (2010). Olfactory signalling in vertebrates and insects: differences and commonalities. Nature Reviews Neuroscience, 11(3), 188-200.

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Kaupp, U. B.1, Author           
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1Department of Molecular Sensory Systems, Center of Advanced European Studies and Research (caesar), Max Planck Society, ou_2173679              

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 Abstract: Vertebrates and insects have evolved complex repertoires of chemosensory receptors to detect and distinguish odours. With a few exceptions, vertebrate chemosensory receptors belong to the family of G protein-coupled receptors that initiate a cascade of cellular signalling events and thereby electrically excite the neuron. Insect receptors, which are structurally and genetically unrelated to vertebrate receptors, are a complex of two distinct molecules that serves both as a receptor for the odorant and as an ion channel that is gated by binding of the odorant. Metabotropic signalling in vertebrates provides a rich panoply of positive and negative regulation, whereas ionotropic signalling in insects enhances processing speed

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 Dates: 2010
 Publication Status: Published in print
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 Identifiers: ISI: ISI:000274653500011
ISSN: 1471-0048
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Title: Nature Reviews Neuroscience
  Alternative Title : Nat. Rev. Neurosci.
Source Genre: Journal
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Pages: - Volume / Issue: 11 (3) Sequence Number: - Start / End Page: 188 - 200 Identifier: -