English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Reversible light switch for macrocycle mobility in a DNA rotaxane

Lohmann, F., Ackermann, D., & Famulok, M. (2012). Reversible light switch for macrocycle mobility in a DNA rotaxane. Journal of the American Chemical Society, 134(29), 11884-7. doi:10.1021/ja3042096.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0028-640B-9 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0028-640C-7
Genre: Journal Article

Files

show Files
hide Files
:
Lohmann-2012-Reversible light swi.pdf (Any fulltext), 2MB
 
File Permalink:
-
Name:
Lohmann-2012-Reversible light swi.pdf
Description:
-
Visibility:
Private
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Description:
-
Description:
-

Creators

show
hide
 Creators:
Lohmann, F., Author
Ackermann, D., Author
Famulok, M.1, Author
Affiliations:
1External Organizations, ou_persistent22              

Content

show
hide
Free keywords: Base Sequence DNA/*chemistry Light Macrocyclic Compounds/*chemistry Molecular Sequence Data Nanostructures/chemistry Rotaxanes/*chemistry
 Abstract: A recent trend in DNA nanotechnology consists of the assembly of architectures with dynamic properties that can be regulated by employing external stimuli. Reversible processes are important for implementing molecular motion into DNA architectures as they allow for the regeneration of the original state. Here we describe two different approaches for the reversible switching of a double-stranded DNA rotaxane architecture from a stationary pseudorotaxane mode into a state with movable components. Both states only marginally differ in their respective topologies but their mechanical properties are fundamentally different. In the two approaches, the switching operation is based on strand-displacement reactions. One of them employs toehold-extended oligodeoxynucleotides whereas in the other one the switching is achieved by light-irradiation. In both cases, multiple back and forth switching between the stationary and the mobile states was achieved in nearly quantitative fashion. The ability to reversibly operate mechanical motion in an interlocked DNA nanostructure opens exciting new avenues in DNA nanotechnology.

Details

show
hide
Language(s):
 Dates: 2012
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: Other: 22780815
DOI: 10.1021/ja3042096
ISSN: 1520-5126 (Electronic)
ISSN: 0002-7863 (Linking)
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Journal of the American Chemical Society
  Alternative Title : J. Am. Chem. Soc.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 134 (29) Sequence Number: - Start / End Page: 11884 - 7 Identifier: -