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  A trifluoromethylphenyl diazirine-based SecinH3 photoaffinity probe

Albertoni, B., Hannam, J. S., Ackermann, D., Schmitz, A., & Famulok, M. (2012). A trifluoromethylphenyl diazirine-based SecinH3 photoaffinity probe. Chemical Communications, 48(9), 1272-4. doi:10.1039/c2cc16477a.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0028-641A-7 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-002B-612D-B
Genre: Journal Article

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Albertoni-2012-A trifluoromethylphenyl diaziri.pdf (Any fulltext), 2MB
 
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 Creators:
Albertoni, B., Author
Hannam, J. S., Author
Ackermann, D., Author
Schmitz, A., Author
Famulok, M.1, Author
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1External Organizations, ou_persistent22              

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Free keywords: Azirines/chemical synthesis/*chemistry GTPase-Activating Proteins/analysis HEK293 Cells Humans Photoaffinity Labels/chemical synthesis/*chemistry Triazoles/chemical synthesis/*chemistry
 Abstract: The synthesis of a trifluoromethylphenyl diazirine photoaffinity probe of the cytohesin inhibitor SecinH3 is described. The probe exhibits improved labelling efficiency over a benzophenone-based probe and thus is more suitable for photoaffinity labelling in complex biological samples.

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 Dates: 2012
 Publication Status: Issued
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 Identifiers: Other: 22179571
DOI: 10.1039/c2cc16477a
ISSN: 1364-548X (Electronic)
ISSN: 1359-7345 (Linking)
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Title: Chemical Communications
  Alternative Title : Chem. Commun. (Camb.)
Source Genre: Journal
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Pages: - Volume / Issue: 48 (9) Sequence Number: - Start / End Page: 1272 - 4 Identifier: -