English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Mirror motor activity during right-hand contractions and its relation to white matter in the posterior midbody of the corpus callosum

Sehm, B., Steele, C., Villringer, A., & Ragert, P. (2016). Mirror motor activity during right-hand contractions and its relation to white matter in the posterior midbody of the corpus callosum. Cerebral Cortex, 26(11), 4347-4355. doi:10.1093/cercor/bhv217.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0028-7BB9-6 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-6075-D
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Sehm, Bernhard1, 2, Author              
Steele, Christopher1, Author              
Villringer, Arno1, 2, Author              
Ragert, Patrick1, Author              
Affiliations:
1Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
2Clinic for Cognitive Neurology, University of Leipzig, Germany, ou_persistent22              

Content

show
hide
Free keywords: Dorsal premotor cortex; Mirror EMG activity; Motor overflow; Primary motor cortex; Supplementary motor area
 Abstract: Cortical activity during simple unimanual actions is typically lateralized to contralateral sensorimotor areas, while a more bilateral pattern is observed with an increase in task demands. In parallel, increasing task demands are associated with subtle mirror muscle activity in the resting hand, implying a relative loss in motor selectivity. The corpus callosum (CC) is crucially involved in unimanual tasks by mediating both facilitatory and inhibitory interactions between bilateral motor cortical systems, but its association with mirror motor activity is yet unknown. Here, we used diffusion-weighted imaging and bilateral electromyographic (EMG) measurements during a unimanual task to investigate potential relationships between white matter microstructure of the CC and mirror EMG activity. Participants performed an unimanual pinch force task with both hands alternatively. Four parametrically increasing force levels were exerted while EMG activity was recorded bilaterally from first dorsal interosseus muscles. Consistent with previous findings, mirror EMG activity increased as a function of force. Additionally, there was a significant relationship between the slope of increasing mirror EMG during right-hand contractions and fractional anisotropy in transcallosal fibers connecting both M1. No significant relationships were found for fibers connecting dorsal premotor cortices or supplementary motor area, indicating the local specificity of the observed brain–physiology relationship.

Details

show
hide
Language(s): eng - English
 Dates: 2015-09-222016-11
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1093/cercor/bhv217
PMID: 26400922
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Cerebral Cortex
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: New York, NY : Oxford University Press
Pages: - Volume / Issue: 26 (11) Sequence Number: - Start / End Page: 4347 - 4355 Identifier: ISSN: 1047-3211
CoNE: /journals/resource/954925592440