hide
Free keywords:
CHROMOSOME SEGREGATION; SELF-ORGANIZATION; BACILLUS-SUBTILIS; B.
SUBTILIS; DNA; GENOME; RECRUITMENT; REPLICATION; CHROMATIDS; PARB
Abstract:
Two studies using chromosome conformation capture (3C) analyses in the Gram-positive bacterium Bacillus subtilis have revealed a global pattern of chromosome organization that originates from loading sites of the Smc-ScpAB complex. Loading Smc-ScpAB at a single genomic location is sufficient to promote genome-wide folding of DNA into a well-defined structure.