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  Neurobiology of language recovery after stroke: Lessons from neuroimaging studies

Saur, D., & Hartwigsen, G. (2012). Neurobiology of language recovery after stroke: Lessons from neuroimaging studies. Archives of Physical Medicine and Rehabilitation, 93(Suppl.), S15-S25. doi:10.1016/j.apmr.2011.03.036.

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 Creators:
Saur, Dorothee1, Author
Hartwigsen, Gesa1, Author              
Affiliations:
1Language & Aphasia Laboratory, Clinic for Cognitive Neurology, University of Leipzig, Germany, ou_persistent22              

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Free keywords: Aphasia; Magnetic resonance imaging; Rehabilitation; Stroke
 Abstract: Language is organized in large-scale, predominantly left-lateralized, temporo-parieto-frontal networks in the human brain. After focal brain damage (eg, ischemic stroke), this network organization enables the brain to adaptively reorganize language functions in order to compensate lesion effects. Here, we summarize how structural and functional neuroimaging methods contribute to the current understanding of loss and recovery of language functions after stroke. This includes voxelwise lesion-behavior mapping, functional imaging for mapping reorganizational mechanisms from acute to chronic stroke, as well as imaging based outcome prediction. The review is complemented by an introductory section on language organization in the healthy brain.

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Language(s): eng - English
 Dates: 2011-12-242012-01
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.apmr.2011.03.036
PMID: 22202187
 Degree: -

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Title: Archives of Physical Medicine and Rehabilitation
Source Genre: Journal
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Publ. Info: Philadelphia, PA, USA : Saunders
Pages: - Volume / Issue: 93 (Suppl.) Sequence Number: - Start / End Page: S15 - S25 Identifier: ISSN: 0003-9993
CoNE: https://pure.mpg.de/cone/journals/resource/0003-9993