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  Glutamate receptor channel signatures

Sprengel, R., Aronoff, R., Völkner, M., Schmitt, B., Mosbach, R., & Kuner, T. (2001). Glutamate receptor channel signatures. Trends in Pharmacological Sciences, 22(1), 7-10. doi:10.1016/S0165-6147(00)01588-1.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0029-2318-2 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0029-2319-F
Genre: Journal Article
Alternative Title : Glutamate receptor channel signatures

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TrendsPharmacolSci_22_2001_7.pdf (Any fulltext), 54KB
 
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 Creators:
Sprengel, Rolf1, Author              
Aronoff, Rachel1, Author              
Völkner, Michaela, Author
Schmitt, Bertram, Author
Mosbach, Raphael, Author
Kuner, Thomas1, 2, 3, 4, 5, Author              
Affiliations:
1Department of Molecular Neurobiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497704              
2Interdisciplinary WIN-Research Group on Olfactory Dynamics, Max Planck Institute for Medical Research, Max Planck Society, ou_1497717              
3Synaptic Transmission MNTB, Max Planck Institute for Medical Research, Max Planck Society, ou_1497745              
4Synaptic Transmission, Max Planck Institute for Medical Research, Max Planck Society, ou_1497744              
5Department of Cell Physiology, Max Planck Institute for Medical Research, Max Planck Society, ou_1497701              

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Free keywords: NMDA; AMPA; Kainate; Conserved motif; Open reading frames
 Abstract: Genes encoding glutamate receptor channel subunits were identified in genomes from Drosophila melanogaster and Caenorhabditis elegans by homology search with amino acid sequences that participate in the conserved channel pore. The predicted sequences of the putative glutamate receptor subunits revealed a distinct channel pore signature for each receptor subtype and for most of them, related members were found in C. elegans and Drosophila.

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Title: Trends in Pharmacological Sciences
Source Genre: Journal
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Publ. Info: Cambridge, UK : Elsevier Current Trends
Pages: - Volume / Issue: 22 (1) Sequence Number: - Start / End Page: 7 - 10 Identifier: ISSN: 0165-6147
CoNE: https://pure.mpg.de/cone/journals/resource/954925481621