ausblenden:
Schlagwörter:
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Zusammenfassung:
Glucocorticoids are thought to play an important role in parturition.
Two recent articles by Di Stefano et al. in the Archives and Wang et al.
in this issue of Science Signaling reveal novel mechanisms by which
glucocorticoid signaling can drive the epigenetic and transcriptional
machinery to induce molecules involved in parturition, including the
neuropeptide corticotropin-releasing hormone (CRH), the enzyme
cyclooxygenase-2 (COX-2), and the autacoid hormone prostaglandin E2.
These findings contribute to our understanding of how glucocorticoids
may regulate human parturition.
