Deutsch
 
Hilfe Datenschutzhinweis Impressum
  DetailsucheBrowse

Datensatz

DATENSATZ AKTIONENEXPORT
  Is it worth the effort?: Novel insights into obesity-associated alterations in cost-benefit decision-making

Mathar, D., Horstmann, A., Pleger, B., Villringer, A., & Neumann, J. (2016). Is it worth the effort?: Novel insights into obesity-associated alterations in cost-benefit decision-making. Frontiers in Behavioral Neuroscience, 9: 360. doi:10.3389/fnbeh.2015.00360.

Item is

Basisdaten

einblenden: ausblenden:
Genre: Zeitschriftenartikel

Dateien

einblenden: Dateien
ausblenden: Dateien
:
Mathar_2016.pdf (Verlagsversion), 2MB
Name:
Mathar_2016.pdf
Beschreibung:
-
OA-Status:
Sichtbarkeit:
Öffentlich
MIME-Typ / Prüfsumme:
application/pdf / [MD5]
Technische Metadaten:
Copyright Datum:
-
Copyright Info:
-
Lizenz:
-

Externe Referenzen

einblenden:
ausblenden:
externe Referenz:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4709417/ (beliebiger Volltext)
Beschreibung:
-
OA-Status:

Urheber

einblenden:
ausblenden:
 Urheber:
Mathar, David1, 2, Autor           
Horstmann, Annette1, 2, Autor           
Pleger, Burkhard1, 2, 3, Autor           
Villringer, Arno1, 2, 3, 4, Autor           
Neumann, Jane1, 2, Autor           
Affiliations:
1Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
2Integrated Research and Treatment Center Adiposity Diseases, University of Leipzig, Germany, ou_persistent22              
3Clinic for Cognitive Neurology, University of Leipzig, Germany, ou_persistent22              
4Berlin School of Mind and Brain, Humboldt University Berlin, Germany, ou_persistent22              

Inhalt

einblenden:
ausblenden:
Schlagwörter: Obesity; Cost-benefit decision-making; Eating behavior; Effort; Reward system; Gender; Voxel-based morphometry
 Zusammenfassung: Cost-benefit decision-making entails the process of evaluating potential actions according to the trade-off between the expected benefit (reward) and the anticipated costs (effort). Recent research revealed that dopaminergic transmission within the fronto-striatal circuitry strongly modulates cost-benefit decision-making. Alterations within the dopaminergic fronto-striatal system have been associated with obesity, but little is known about cost-benefit decision-making differences in obese compared with lean individuals. With a newly developed experimental task we investigate obesity-associated alterations in cost-benefit decision-making, utilizing physical effort by handgrip-force exertion and both food and non-food rewards. We relate our behavioral findings to alterations in local grey matter volume assessed by structural MRI. Obese compared with lean subjects were less willing to engage in physical effort in particular for high-caloric sweet snack food. The amount of effort exertion was thereby negatively associated with subjects’ individual levels of chronic stress and punishment sensitivity. Further, self-reported body dissatisfaction negatively correlated with the willingness to invest effort for sweet snacks in obese men. On a structural level, obesity was associated with reductions in grey matter volume in bilateral prefrontal cortex. Nucleus accumbens volume positively correlated with task-induced implicit food craving. Our results challenge the common notion that obese individuals are willing to work harder to obtain high-caloric food and emphasize the need for further exploration of the underlying neural mechanisms regarding cost-benefit decision-making differences in obesity.

Details

einblenden:
ausblenden:
Sprache(n): eng - English
 Datum: 2015-10-012015-12-142016-01-12
 Publikationsstatus: Online veröffentlicht
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: Expertenbegutachtung
 Identifikatoren: DOI: 10.3389/fnbeh.2015.00360
PMID: 26793079
PMC: PMC4709417
Anderer: eCollection 2015
 Art des Abschluß: -

Veranstaltung

einblenden:

Entscheidung

einblenden:

Projektinformation

einblenden:

Quelle 1

einblenden:
ausblenden:
Titel: Frontiers in Behavioral Neuroscience
  Kurztitel : Front Behav Neurosci
Genre der Quelle: Zeitschrift
 Urheber:
Affiliations:
Ort, Verlag, Ausgabe: -
Seiten: - Band / Heft: 9 Artikelnummer: 360 Start- / Endseite: - Identifikator: Anderer: 1662-5153
CoNE: https://pure.mpg.de/cone/journals/resource/1662-5153