English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Is it worth the effort?: Novel insights into obesity-associated alterations in cost-benefit decision-making

Mathar, D., Horstmann, A., Pleger, B., Villringer, A., & Neumann, J. (2016). Is it worth the effort?: Novel insights into obesity-associated alterations in cost-benefit decision-making. Frontiers in Behavioral Neuroscience, 9: 360. doi:10.3389/fnbeh.2015.00360.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0029-4D94-7 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-1E43-1
Genre: Journal Article

Files

show Files
hide Files
:
Mathar_2016.pdf (Publisher version), 2MB
Name:
Mathar_2016.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Description:
-

Creators

show
hide
 Creators:
Mathar, David1, 2, Author              
Horstmann, Annette1, 2, Author              
Pleger, Burkhard1, 2, 3, Author              
Villringer, Arno1, 2, 3, 4, Author              
Neumann, Jane1, 2, Author              
Affiliations:
1Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
2Integrated Research and Treatment Center Adiposity Diseases, University of Leipzig, Germany, ou_persistent22              
3Clinic for Cognitive Neurology, University of Leipzig, Germany, ou_persistent22              
4Berlin School of Mind and Brain, Humboldt University Berlin, Germany, ou_persistent22              

Content

show
hide
Free keywords: Obesity; Cost-benefit decision-making; Eating behavior; Effort; Reward system; Gender; Voxel-based morphometry
 Abstract: Cost-benefit decision-making entails the process of evaluating potential actions according to the trade-off between the expected benefit (reward) and the anticipated costs (effort). Recent research revealed that dopaminergic transmission within the fronto-striatal circuitry strongly modulates cost-benefit decision-making. Alterations within the dopaminergic fronto-striatal system have been associated with obesity, but little is known about cost-benefit decision-making differences in obese compared with lean individuals. With a newly developed experimental task we investigate obesity-associated alterations in cost-benefit decision-making, utilizing physical effort by handgrip-force exertion and both food and non-food rewards. We relate our behavioral findings to alterations in local grey matter volume assessed by structural MRI. Obese compared with lean subjects were less willing to engage in physical effort in particular for high-caloric sweet snack food. The amount of effort exertion was thereby negatively associated with subjects’ individual levels of chronic stress and punishment sensitivity. Further, self-reported body dissatisfaction negatively correlated with the willingness to invest effort for sweet snacks in obese men. On a structural level, obesity was associated with reductions in grey matter volume in bilateral prefrontal cortex. Nucleus accumbens volume positively correlated with task-induced implicit food craving. Our results challenge the common notion that obese individuals are willing to work harder to obtain high-caloric food and emphasize the need for further exploration of the underlying neural mechanisms regarding cost-benefit decision-making differences in obesity.

Details

show
hide
Language(s): eng - English
 Dates: 2015-10-012015-12-142016-01-12
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.3389/fnbeh.2015.00360
PMID: 26793079
PMC: PMC4709417
Other: eCollection 2015
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Frontiers in Behavioral Neuroscience
  Abbreviation : Front Behav Neurosci
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 9 Sequence Number: 360 Start / End Page: - Identifier: Other: 1662-5153
CoNE: https://pure.mpg.de/cone/journals/resource/1662-5153