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  Data in support of substrate flexibility of a mutated acyltransferase domain and implications for polyketide biosynthesis

Klopries, S., Bravo-Rodriguez, K., Koopmans, K. R. M., Sundermann, U., Yahiaoui, S., Arens, J., et al. (2015). Data in support of substrate flexibility of a mutated acyltransferase domain and implications for polyketide biosynthesis. Data in Brief, 5, 528-536. doi:10.1016/j.dib.2015.09.052.

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 Creators:
Klopries, Stephan1, Author
Bravo-Rodriguez, Kenny2, Author              
Koopmans, Kyra R. M.1, Author
Sundermann, Uschi3, Author
Yahiaoui, Samir4, Author
Arens, Julia1, Author
Kushnir, Susanna1, Author
Sanchez Garcia, Elsa2, Author              
Schulz, Frank1, Author
Affiliations:
1Fakultät für Chemie und Biochemie, Organische Chemie 1, Ruhr-Universität Bochum, Universitätsstraße 150, 44780 Bochum, Germany, ou_persistent22              
2Research Group Sánchez-García, Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1950289              
3Dr. Fooke-Achterrath Laboratorien GmbH, Habichtweg 16, 41468 Neuss, Germany, ou_persistent22              
4Université de Caen Basse-Normandie, Centre d’Etudes et de Recherche sur le Médicament de Normandie, 14032 Caen, France, ou_persistent22              

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 Abstract: Enzyme-directed mutasynthesis is an emerging strategy for the targeted derivatization of natural products. Here, data on the synthesis of malonic acid derivatives for feeding studies in Saccharopolyspora erythraea , the mutagenesis of DEBS and bioanalytical data on the experimental investigation of studies on the biosynthetic pathway towards erythromycin are presented.

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Language(s): eng - English
 Dates: 2015-09-302015-04-292015-09-302015-10-142015-12-01
 Publication Status: Published in print
 Pages: 9
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.dib.2015.09.052
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Title: Data in Brief
Source Genre: Journal
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Publ. Info: Dordrecht : Elsevier
Pages: - Volume / Issue: 5 Sequence Number: - Start / End Page: 528 - 536 Identifier: ISSN: 2352-3409
CoNE: https://pure.mpg.de/cone/journals/resource/2352-3409