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  Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA

Woerner, A. C., Frottin, F., Hornburg, D., Feng, L. R., Meissner, F., Patra, M., et al. (2016). Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA. Science, 351(6269), 173-176.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-002B-0491-8 Version Permalink: https://hdl.handle.net/11858/00-001M-0000-002D-3046-6
Genre: Journal Article

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Data from the mass spectrometry analysis described in this manuscript can be found in the supplementary materials.
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http://science.sciencemag.org/content/351/6269/173 (Publisher version)
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 Creators:
Woerner, Andreas C.1, Author           
Frottin, Frederic2, Author           
Hornburg, Daniel3, Author           
Feng, Li R.1, Author           
Meissner, Felix4, Author           
Patra, Maria, Author
Tatzelt, Jörg, Author
Mann, Matthias3, Author           
Winklhofer, Konstanze F.1, Author           
Hartl, F. Ulrich1, Author           
Hipp, Mark S.1, Author           
Affiliations:
1Hartl, Franz-Ulrich / Cellular Biochemistry, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565152              
2Hartl, Franz-Ulrich / Cellular Biochemistry, Max Planck Institute of Biochemistry, Max Planck Society, ou_persistent22              
3Mann, Matthias / Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565159              
4Meissner, Felix / Experimental Systems Immunology, Max Planck Institute of Biochemistry, Max Planck Society, ou_2149678              

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 Dates: 2015-08-072015-11-112015-12-032016-01-08
 Publication Status: Issued
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 Rev. Type: Peer
 Identifiers: PMID: 26634439
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Project name : Toxic Protein AGgregation in Neurodegeneration (ToPAG)
Grant ID : 318987
Funding program : Funding Programme 7 (FP7)
Funding organization : European Commission (EC)

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Title: Science
Source Genre: Journal
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Pages: - Volume / Issue: 351 (6269) Sequence Number: - Start / End Page: 173 - 176 Identifier: DOI: 10.1126/science.aad2033