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  Trends in microfluidics with complex fluids

Pfohl, T., Mugele, F., Seemann, R., & Herminghaus, S. (2003). Trends in microfluidics with complex fluids. ChemPhysChem, 4(12), 1291-1298. doi:10.1002/cphc.200300847.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0029-A9EF-6 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0029-A9F0-D
Genre: Journal Article

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 Creators:
Pfohl, Thomas1, Author              
Mugele, Frieder2, Author
Seemann, Ralf3, Author              
Herminghaus, Stephan4, Author              
Affiliations:
1Group Dynamics of biological matter, Department of Dynamics of Complex Fluids, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society, ou_2063313              
2External Organizations, ou_persistent22              
3Group Geometry of Fluid Interfaces, Department of Dynamics of Complex Fluids, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society, ou_2063311              
4Group Granular matter and irreversibility, Department of Dynamics of Complex Fluids, Max Planck Institute for Dynamics and Self-Organization, Max Planck Society, ou_2063306              

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 Abstract: The rapid developments in biotechnology create a great demand for fluid handling systems on the nano- and picoliter scale. The characterization of minute quantities of DNA or protein samples requires highly integrated, automated, and miniaturized “total analysis systems” (μ-TAS). The small scales necessitate new concepts for devices both from a technological and from a fundamental physical point of view. Here, we describe recent trends in both areas. New technologies include soft lithography, chemical, and topographical structuring of surfaces in order to define pathways for liquids, as well as electrowetting for manipulation purposes. Fundamentally, the interplay between geometric confinement and the size of biological macromolecules gives rise to complex dynamic behavior. The combination of both fluorescence imaging and scattering techniques allows for detailed insight into the dynamics of individual molecules and into their self-assembly into supramolecular aggregates.

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Language(s): eng - English
 Dates: 2003
 Publication Status: Published in print
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 Rev. Method: -
 Identifiers: DOI: 10.1002/cphc.200300847
BibTex Citekey: pfohl_trends_2003
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Title: ChemPhysChem
Source Genre: Journal
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Publ. Info: Weinheim, Germany : Wiley-VCH
Pages: - Volume / Issue: 4 (12) Sequence Number: - Start / End Page: 1291 - 1298 Identifier: ISSN: 1439-4235
CoNE: /journals/resource/954925409790